# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3755536 | Binding | Displacement of 125I-labeled [Nle4,DPhe7]-alpha-MSH from human melanocortin 3 receptor expressed in HEK293 cells incubated for 40 mins by gamma counting analysis | Homo sapiens | 5 | ALA3751760 | cell-based format | Scientific Literature | |
2. | ALA3755537 | Binding | Displacement of 125I-labeled [Nle4,DPhe7]-alpha-MSH from human melanocortin 4 receptor expressed in HEK293 cells incubated for 40 mins by gamma counting analysis | Homo sapiens | 5 | ALA3751760 | cell-based format | Scientific Literature | |
3. | ALA3755538 | Binding | Displacement of 125I-labeled [Nle4,DPhe7]-alpha-MSH from human melanocortin 5 receptor expressed in HEK293 cells incubated for 40 mins by gamma counting analysis | Homo sapiens | 4 | ALA3751760 | cell-based format | Scientific Literature | |
4. | ALA3755539 | Functional | Agonist activity at human melanocortin 1 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation incubated for 3 mins in presence of IBMX | Homo sapiens | 5 | ALA3751760 | cell-based format | Scientific Literature | |
5. | ALA3755540 | Functional | Agonist activity at human melanocortin 3 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation incubated for 3 mins in presence of IBMX | Homo sapiens | 4 | ALA3751760 | cell-based format | Scientific Literature | |
6. | ALA3755541 | Functional | Agonist activity at human melanocortin 4 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation incubated for 3 mins in presence of IBMX | Homo sapiens | 4 | ALA3751760 | cell-based format | Scientific Literature | |
7. | ALA3755542 | Functional | Agonist activity at human melanocortin 5 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation incubated for 3 mins in presence of IBMX | Homo sapiens | 4 | ALA3751760 | cell-based format | Scientific Literature | |
8. | ALA3755543 | Binding | Displacement of 125I-labeled [Nle4,DPhe7]-alpha-MSH from human melanocortin 1 receptor expressed in HEK293 cells at 10 uM incubated for 40 mins by gamma counting analysis | Homo sapiens | 1 | ALA3751760 | cell-based format | Scientific Literature | |
9. | ALA3755544 | Functional | Agonist activity at human melanocortin 1 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP accumulation incubated for 3 mins relative to MT-2 | Homo sapiens | 4 | ALA3751760 | cell-based format | Scientific Literature | |
10. | ALA3755545 | Functional | Agonist activity at human melanocortin 3 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP accumulation incubated for 3 mins relative to MT-2 | Homo sapiens | 3 | ALA3751760 | cell-based format | Scientific Literature | |
11. | ALA3755547 | Functional | Agonist activity at human melanocortin 5 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP accumulation incubated for 3 mins relative to MT-2 | Homo sapiens | 3 | ALA3751760 | cell-based format | Scientific Literature | |
12. | ALA3755737 | Binding | Selectivity ratio of EC50 for human melanocortin 4 receptor expressed in HEK293 cells to EC50 for human melanocortin 3 receptor expressed in HEK293 cells | Homo sapiens | 1 | ALA3751760 | cell-based format | Scientific Literature |