# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4420451 | Binding | Inhibition of C-Myc/DDK-tagged human recombinant SYNJ2 expressed in HEK293T cells assessed as reduction in 5'-phosphatase activity incubated for 8 mins using fluorescently-labeled PI(3,4)P2 probe and Tapp1 PH-domain as detector protein by fluorescence polarization competitive assay | Homo sapiens | 24 | ALA4420065 | cell-based format | Patent Bioactivity Data | |
2. | ALA4420452 | Binding | Inhibition of C-Myc/DDK-tagged human recombinant SYNJ1 expressed in HEK293T cells assessed as reduction in 5'-phosphatase activity incubated for 8 mins using fluorescently-labeled PI(3,4)P2 probe and Tapp1 PH-domain as detector protein by fluorescence polarization competitive assay | Homo sapiens | 24 | ALA4420065 | cell-based format | Patent Bioactivity Data | |
3. | ALA4421074 | Binding | Inhibition of C-Myc/DDK-tagged human recombinant SYNJ2 expressed in HEK293T cells assessed as reduction in 5'-phosphatase activity incubated for 8 mins using fluorescently-labeled PI(3,4)P2 probe and Tapp1 PH-domain as detector protein by fluorescence polarization competitive assay | Homo sapiens | 24 | ALA4420077 | cell-based format | Patent Bioactivity Data | |
4. | ALA4421075 | Binding | Inhibition of C-Myc/DDK-tagged human recombinant SYNJ1 expressed in HEK293T cells assessed as reduction in 5'-phosphatase activity incubated for 8 mins using fluorescently-labeled PI(3,4)P2 probe and Tapp1 PH-domain as detector protein by fluorescence polarization competitive assay | Homo sapiens | 24 | ALA4420077 | cell-based format | Patent Bioactivity Data | |
5. | ALA4604861 | Functional | Antimalarial activity against chloroquine-sensitive Plasmodium falciparum 3D7 assessed as reduction in parasite growth at 40 uM incubated for 72 hrs by DAPI staining based fluorescence assay | Plasmodium falciparum | 6 | ALA4602686 | organism-based format | Scientific Literature | |
6. | ALA4604862 | Functional | Antimalarial activity against chloroquine-resistant Plasmodium falciparum Dd2 assessed as reduction in parasite growth at 40 uM incubated for 72 hrs by DAPI staining based fluorescence assay | Plasmodium falciparum | 6 | ALA4602686 | organism-based format | Scientific Literature | |
7. | ALA4604863 | Binding | Inhibition of (CAG)33/FF/HCV/Ren.pA51 mRNA cap-dependent translation assessed as reduction in firefly level at 10 mM after 60 mins by dual luciferase reporter gene assay | Hepacivirus hominis | 6 | ALA4602686 | assay format | Scientific Literature | |
8. | ALA4604864 | Binding | Inhibition of (CAG)33/FF/HCV/Ren.pA51 mRNA cap-independent translation assessed as reduction in renilla level at 10 mM after 60 mins by dual luciferase reporter gene assay | Hepacivirus hominis | 6 | ALA4602686 | assay format | Scientific Literature |