#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4423397	Functional	Antitumor activity against human HCT116 cells xenografted in Balb/c nude mouse assessed as tumor growth inhibition at 50 mg/kg, po qd for 30 days and measured every 3 days by calliper method relative to control	Homo sapiens	2	ALA4422627	organism-based format	Scientific Literature
2.	ALA4423398	Binding	Inhibition of ERK2 (unknown origin) using lipid as substrate after 40 mins by ADP-Glo luminescence assay	Homo sapiens	34	ALA4422627	single protein format	Scientific Literature
3.	ALA4423399	Binding	Inhibition of ERK1 (unknown origin) using lipid as substrate after 40 mins by ADP-Glo luminescence assay	Homo sapiens	5	ALA4422627	single protein format	Scientific Literature
4.	ALA4423400	Functional	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	Homo sapiens	6	ALA4422627	cell-based format	Scientific Literature
5.	ALA4423401	Functional	Antiproliferative activity against human WM266.4 cells after 72 hrs by MTT assay	Homo sapiens	6	ALA4422627	cell-based format	Scientific Literature
6.	ALA4423402	Functional	Antiproliferative activity against human SW626 cells after 72 hrs by MTT assay	Homo sapiens	6	ALA4422627	cell-based format	Scientific Literature
7.	ALA4423403	Functional	Antiproliferative activity against human COLO205 cells after 72 hrs by MTT assay	Homo sapiens	6	ALA4422627	cell-based format	Scientific Literature
8.	ALA4423404	Functional	Induction of apoptosis in human HCT116 cells assessed as increase in condense bright apoptotic nuclei formation at 1 uM by Hoechst 33258 staining-based assay	Homo sapiens	2	ALA4422627	cell-based format	Scientific Literature
9.	ALA4423405	ADME	Cytotoxicity against human NCM460 cells assessed as reduction in cell viability at 10000 nM after 72 hrs by MTT assay	Homo sapiens	2	ALA4422627	cell-based format	Scientific Literature
10.	ALA4423406	Functional	Induction of apoptosis in human HCT116 cells assessed as early apoptotic cells at 1 uM after 72 hrs by annexin V-FITC and propidium iodide staining based flow cytometric analysis (Rvb = 3.88%)	Homo sapiens	2	ALA4422627	cell-based format	Scientific Literature
11.	ALA4423407	Functional	Induction of apoptosis in human HCT116 cells assessed as late apoptotic cells at 1 uM after 72 hrs by annexin V-FITC and propidium iodide staining based flow cytometric analysis (Rvb = 1.20%)	Homo sapiens	2	ALA4422627	cell-based format	Scientific Literature
12.	ALA4423408	Functional	Induction of apoptosis in human HCT116 cells assessed as necrotic cells at 1 uM after 72 hrs by annexin V-FITC and propidium iodide staining based flow cytometric analysis (Rvb = 0.21%)	Homo sapiens	2	ALA4422627	cell-based format	Scientific Literature
13.	ALA4423409	Functional	Induction of apoptosis in human HCT116 cells assessed as viable cells at 1 uM after 72 hrs by annexin V-FITC and propidium iodide staining based flow cytometric analysis (Rvb = 94.3%)	Homo sapiens	2	ALA4422627	cell-based format	Scientific Literature
14.	ALA4423410	Functional	Cell cycle arrest in human HCT116 cells assessed as accumulation at G0/G1 phase at 1 uM after 72 hrs by annexin V-FITC and propidium iodide staining based flow cytometric analysis (Rvb = 44.3%)	Homo sapiens	2	ALA4422627	cell-based format	Scientific Literature
15.	ALA4423411	Functional	Cell cycle arrest in human HCT116 cells assessed as accumulation at G2/M phase at 1 uM after 72 hrs by annexin V-FITC and propidium iodide staining based flow cytometric analysis (Rvb = 43.5%)	Homo sapiens	2	ALA4422627	cell-based format	Scientific Literature
16.	ALA4423417	Toxicity	Toxicity against Balb/c nude mouse xenografted with human HCT116 cells assessed as reduction in body weight at 50 mg/kg, po qd for 30 days and measured every 3 days	Mus musculus	1	ALA4422627	organism-based format	Scientific Literature
17.	ALA4423418	Binding	Inhibition of ERK1/2 phosphorylation at Thr202/Tyr204 residues in human HCT116 cells by Western blot analysis	Homo sapiens	1	ALA4422627	cell-based format	Scientific Literature
18.	ALA4423419	Binding	Inhibition of ERK1/2 in human HCT116 cells assessed as reduction in RSK phosphorylation at Thr359/Ser363 residues by Western blot analysis	Homo sapiens	1	ALA4422627	cell-based format	Scientific Literature
19.	ALA4423420	Functional	Antiproliferative activity against human K562 cells after 72 hrs by MTT assay	Homo sapiens	7	ALA4422627	cell-based format	Scientific Literature