# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4367975 | P | Solubility of the compound in MeOH | 7 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA4367976 | P | Solubility of the compound at 30 uM in NDE medium containing 0.1% DMSO | 7 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA4367977 | B | Positive allosteric modulator activity at rat alpha1beta3 GABA-A receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced chloride current at 30 uM co-applied with GABA at concentration of EC3-5 at -60 mV holding potential by two-microelectrode voltage clamp method relative to control | Rattus norvegicus | 9 | cell-based format | Scientific Literature | ||
4. | ALA4367978 | B | Positive allosteric modulator activity at rat alpha1beta3 GABA-A receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced chloride current at 10 uM co-applied with GABA at concentration of EC3-5 at -60 mV holding potential by two-microelectrode voltage clamp method relative to control | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
5. | ALA4367979 | P | Solubility of the compound in DMSO | 7 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA4367980 | B | Positive allosteric modulator activity at rat alpha1beta3 GABA-A receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced chloride current at 1 to 30 uM co-applied with GABA at concentration of EC3-5 at -60 mV holding potential by two-microelectrode voltage clamp method relative to control | Rattus norvegicus | 5 | cell-based format | Scientific Literature |