| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4324542 | B | Protac activity against VHL/MEK1 in human HT-29 cells harboring BRAF V600E variant assessed as degradation of MEK1 at 0.3 to 3 uM after 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4324543 | B | Protac activity against VHL/MEK2 in human HT-29 cells harboring BRAF V600E variant assessed as degradation of MEK2 at 0.3 to 3 uM after 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA4712205 | F | Antiproliferative activity against human HT-29 cells incubated for 3 days by WST8 assay | Homo sapiens | 49 | cell-based format | Scientific Literature |
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