# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4374304 | Binding | Protac activity at CRBN/ IKZF1 in human MM1S cells assessed as IKZF1 degradation by measuring IKZF1/tubulin ratio at 0.1 uM after 16 hrs by Western blot analysis relative to tubulin | Homo sapiens | 7 | ALA4373656 | cell-based format | Scientific Literature | |
2. | ALA4666437 | Binding | Protac activity at VHL/CRBN in HEK293 cells assessed as pVHL19 protein abundance at 1 uM after 4 hrs by Western blot analysis relative to DMSO | Homo sapiens | 3 | ALA4665633 | cell-based format | Scientific Literature | |
3. | ALA4666440 | Binding | Protac activity at VHL/CRBN in HEK293 cells assessed as pVHL19 protein abundance at 1 uM after 24 hrs by Western blot analysis relative to DMSO | Homo sapiens | 3 | ALA4665633 | cell-based format | Scientific Literature | |
4. | ALA4666443 | Binding | Protac activity at VHL/CRBN in HEK293 cells assessed as pVHL30 protein abundance at 1 uM after 4 hrs by Western blot analysis relative to DMSO | Homo sapiens | 3 | ALA4665633 | cell-based format | Scientific Literature | |
5. | ALA4666446 | Binding | Protac activity at VHL/CRBN in HEK293 cells assessed as pVHL30 protein abundance at 1 uM after 24 hrs by Western blot analysis relative to DMSO | Homo sapiens | 3 | ALA4665633 | cell-based format | Scientific Literature | |
6. | ALA4666449 | Binding | Protac activity at VHL/CRBN in HEK293 cells assessed as CRBN protein abundance at 1 uM after 4 hrs by Western blot analysis relative to DMSO | Homo sapiens | 3 | ALA4665633 | cell-based format | Scientific Literature | |
7. | ALA4666452 | Binding | Protac activity at VHL/CRBN in HEK293 cells assessed as CRBN protein abundance at 1 uM after 24 hrs by Western blot analysis relative to DMSO | Homo sapiens | 3 | ALA4665633 | cell-based format | Scientific Literature | |
8. | ALA4666453 | Binding | Protac activity at VHL/CRBN in HEK293 cells assessed as pVHL19 protein abundance after 4 hrs by Western blot analysis relative to DMSO | Homo sapiens | 2 | ALA4665633 | cell-based format | Scientific Literature | |
9. | ALA4666462 | Binding | Protac activity at VHL/CRBN in HEK293 cells assessed as pVHL30 protein abundance after 4 hrs by Western blot analysis relative to DMSO | Homo sapiens | 2 | ALA4665633 | cell-based format | Scientific Literature | |
10. | ALA4666471 | Binding | Protac activity at VHL/CRBN in HEK293 cells assessed as CRBN protein abundance after 4 hrs by Western blot analysis relative to DMSO | Homo sapiens | 2 | ALA4665633 | cell-based format | Scientific Literature | |
11. | ALA4666484 | Binding | Protac activity at VHL/CRBN in human HeLa cells assessed as pVHL19 protein abundance at 1 uM after 24 hrs by Western blot analysis relative to DMSO | Homo sapiens | 3 | ALA4665633 | cell-based format | Scientific Literature | |
12. | ALA4666489 | Binding | Protac activity at VHL/CRBN in human HeLa cells assessed as pVHL30 protein abundance at 1 uM after 24 hrs by Western blot analysis relative to DMSO | Homo sapiens | 3 | ALA4665633 | cell-based format | Scientific Literature | |
13. | ALA4666494 | Binding | Protac activity at VHL/CRBN in human HeLa cells assessed as CRBN protein abundance at 1 uM after 24 hrs by Western blot analysis relative to DMSO | Homo sapiens | 3 | ALA4665633 | cell-based format | Scientific Literature | |
14. | ALA4666495 | Binding | Protac activity at VHL/CRBN in human HeLa cells assessed as pVHL19 protein abundance after 4 hrs by Western blot analysis relative to DMSO | Homo sapiens | 2 | ALA4665633 | cell-based format | Scientific Literature | |
15. | ALA4666503 | Binding | Protac activity at VHL/CRBN in human HeLa cells assessed as pVHL30 protein abundance after 4 hrs by Western blot analysis relative to DMSO | Homo sapiens | 2 | ALA4665633 | cell-based format | Scientific Literature | |
16. | ALA4666511 | Binding | Protac activity at VHL/CRBN in human HeLa cells assessed as CRBN protein abundance after 4 hrs by Western blot analysis relative to DMSO | Homo sapiens | 2 | ALA4665633 | cell-based format | Scientific Literature | |
17. | ALA4666521 | Binding | Protac activity at VHL/CRBN in human HeLa cells assessed as pVHL19 protein abundance at 10 nM after 4 hrs by Western blot analysis relative to DMSO | Homo sapiens | 15 | ALA4665633 | cell-based format | Scientific Literature | |
18. | ALA4666522 | Binding | Protac activity at VHL/CRBN in human HeLa cells assessed as pVHL30 protein abundance at 10 nM after 4 hrs by Western blot analysis relative to DMSO | Homo sapiens | 15 | ALA4665633 | cell-based format | Scientific Literature | |
19. | ALA4666523 | Binding | Protac activity at VHL/CRBN in human HeLa cells assessed as CRBN protein abundance at 10 nM after 4 hrs by Western blot analysis relative to DMSO | Homo sapiens | 15 | ALA4665633 | cell-based format | Scientific Literature | |
20. | ALA4666524 | Binding | Protac activity at VHL/CRBN in human HeLa cells assessed as pVHL19 protein abundance at 1 uM after 4 hrs by Western blot analysis relative to DMSO | Homo sapiens | 15 | ALA4665633 | cell-based format | Scientific Literature |