#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4349047	Binding	Stimulatory activity at sGC in Sprague-Dawley rat thoracic aorta assessed as inhibition of norepinephrine-induced contraction by JZ100 strain guages based isometric analysis	Rattus norvegicus	7	ALA4346707	assay format	Scientific Literature
2.	ALA4349048	Binding	Stimulatory activity at sGC in Sprague-Dawley rat thoracic aorta assessed as inhibition of norepinephrine-induced contraction at 1 uM by JZ100 strain guages based isometric analysis relative to control	Rattus norvegicus	31	ALA4346707	assay format	Scientific Literature
3.	ALA4349050	Functional	Cardioprotective activity in Langendorff perfused Sprague-Dawley rat heart assessed as reduction of coronary perfusion pressure	Rattus norvegicus	4	ALA4346707	tissue-based format	Scientific Literature
4.	ALA4349051	Functional	Cardioprotective activity in Langendorff perfused Sprague-Dawley rat heart assessed as reduction of coronary perfusion pressure at 0.01 to 3 uM relative to control	Rattus norvegicus	3	ALA4346707	tissue-based format	Scientific Literature
5.	ALA4349052	Functional	Cardioprotective activity in Langendorff perfused Sprague-Dawley rat heart assessed as increase in coronary artery relaxation	Rattus norvegicus	3	ALA4346707	tissue-based format	Scientific Literature
6.	ALA4349053	Functional	Potency index. ratio of EC50 of riociguat to EC50 of compound for cardioprotective activity in Langendorff perfused Sprague-Dawley rat heart assessed as increase in coronary artery relaxation	Rattus norvegicus	1	ALA4346707	tissue-based format	Scientific Literature
7.	ALA4349054	ADME	Half life in male Beagle dog at 0.5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature
8.	ALA4349055	ADME	Tmax in male Beagle dog at 0.5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature
9.	ALA4349056	ADME	Cmax in male Beagle dog at 0.5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature
10.	ALA4349057	ADME	AUC (0 to infinity) in male Beagle dog at 0.5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature
11.	ALA4349058	ADME	Apparent clearance in male Beagle dog at 0.5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature
12.	ALA4349059	ADME	Apparent volume of distribution in male Beagle dog at 0.5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature
13.	ALA4349060	ADME	Oral bioavailability (0 to infinity) in male Beagle dog at 0.5 mg/kg by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature
14.	ALA4349061	ADME	Half life in male Beagle dog at 1.5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature
15.	ALA4349062	ADME	Tmax in male Beagle dog at 1.5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature
16.	ALA4349063	ADME	Cmax in male Beagle dog at 1.5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature
17.	ALA4349064	ADME	AUC (0 to infinity) in male Beagle dog at 1.5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature
18.	ALA4349065	ADME	Apparent clearance in male Beagle dog at 1.5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature
19.	ALA4349066	ADME	Apparent volume of distribution in male Beagle dog at 1.5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature
20.	ALA4349067	ADME	Half life in male Beagle dog at 4.5 mg/kg, po by LC-MS/MS analysis	Canis lupus familiaris	1	ALA4346707	organism-based format	Scientific Literature