#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4422841	Binding	Inhibition of wild type recombinant human SHP2 using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-Pro-Pro-Asp-Pro-Ala-Lys as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by Malachite Green-reagent based assay	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
2.	ALA4422842	Binding	Inhibition of wild type recombinant human SHP1 using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-Pro-Pro-Asp-Pro-Ala-Lys as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by Malachite Green-reagent based assay	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
3.	ALA4422843	Binding	Inhibition of recombinant full length human GST-tagged SHP2 E76K mutant using pNPP as substrate pre-incubated for 15 mins before pNPP substrate addition and measured after 15 mins	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
4.	ALA4422844	Binding	Inhibition of recombinant full length human GST-tagged SHP2 PTP domain using pNPP as substrate pre-incubated for 15 mins before pNPP substrate addition and measured after 15 mins	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
5.	ALA4422845	Binding	Mixed type inhibition of human wild-type full length SHP2 assessed as substrate Vmax at 10 uM using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-Pro-Pro-Asp-Pro-Ala-Lys as substrate by Lineweaver-Burk plot analysis (Rvb = 5.55 +/- 0.49 uM/min)	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
6.	ALA4422846	Binding	Mixed type inhibition of human wild-type full length SHP2 assessed as substrate Km at 10 uM using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-Pro-Pro-Asp-Pro-Ala-Lys as substrate by Lineweaver-Burk plot analysis (Rvb = 0.034 +/- 0.012 mM)	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
7.	ALA4422847	Binding	Mixed type inhibition of human wild-type full length SHP2 assessed as substrate Kcat at 10 uM using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-Pro-Pro-Asp-Pro-Ala-Lys as substrate by Lineweaver-Burk plot analysis (Rvb = 3.19 +/- 0.28 Sec'-1)	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
8.	ALA4422848	Binding	Mixed type inhibition of human wild-type full length SHP2 assessed as substrate [Et] at 10 uM using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-Pro-Pro-Asp-Pro-Ala-Lys as substrate by Lineweaver-Burk plot analysis (Rvb = 0.029 uM)	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
9.	ALA4422849	Binding	Mixed type inhibition of human wild-type full length SHP2 assessed as substrate Vmax at 20 uM using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-Pro-Pro-Asp-Pro-Ala-Lys as substrate by Lineweaver-Burk plot analysis (Rvb = 5.55 +/- 0.49 uM/min)	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
10.	ALA4422850	Binding	Mixed type inhibition of human wild-type full length SHP2 assessed as substrate Km at 20 uM using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-Pro-Pro-Asp-Pro-Ala-Lys as substrate by Lineweaver-Burk plot analysis (Rvb = 0.034 +/- 0.012 mM)	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
11.	ALA4422851	Binding	Mixed type inhibition of human wild-type full length SHP2 assessed as substrate Kcat at 20 uM using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-Pro-Pro-Asp-Pro-Ala-Lys as substrate by Lineweaver-Burk plot analysis (Rvb = 3.19 +/- 0.28 Sec'-1)	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
12.	ALA4422852	Binding	Mixed type inhibition of human wild-type full length SHP2 assessed as substrate [Et] at 20 uM using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-Pro-Pro-Asp-Pro-Ala-Lys as substrate by Lineweaver-Burk plot analysis (Rvb = 0.029 uM)	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
13.	ALA4422853	Binding	Mixed type inhibition of human wild-type full length SHP2 assessed as Kcat/Km ratio at 10 uM using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-Pro-Pro-Asp-Pro-Ala-Lys as substrate by Lineweaver-Burk plot analysis (Rvb = 100.3 +/- 25 /mM/sec)	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
14.	ALA4422854	Binding	Mixed type inhibition of human wild-type full length SHP2 assessed as Kcat/Km ratio at 20 uM using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-ProPro-Asp-Pro-Ala-Lys as substrate by Lineweaver-Burk plot analysis (Rvb = 100.3 +/- 25 /mM/sec)	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
15.	ALA4422855	Binding	Binding affinity to full length wild type GST-tagged SHP2 (unknown origin) luminescence spectrometry-based quenching assay	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
16.	ALA4422856	Binding	Binding affinity to His-tagged SHP2 (unknown origin) assessed as melting temperature at 5 uM measured every 50 secs by thermal shift assay (Rvb = 43.5 +/- 0.95 degC)	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
17.	ALA4422857	Binding	Binding affinity to His-tagged SHP2 (unknown origin) assessed as melting temperature at 10 uM measured every 50 secs by thermal shift assay (Rvb = 43.5 +/- 0.95 degC)	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
18.	ALA4422858	Binding	Binding affinity to His-tagged SHP2 (unknown origin) assessed as melting temperature at 60 uM measured every 50 secs by thermal shift assay (Rvb = 43.5 +/- 0.95 degC)	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
19.	ALA4422859	Binding	Binding affinity to full length wild type His-tagged SHP2 (unknown origin) by MST assay	Homo sapiens	1	ALA4422612	single protein format	Scientific Literature
20.	ALA4422860	Binding	Inhibition of SHP2 in mouse Ba/F3 cells assessed as reduction in IL3-stimulated ERK phosphorylation pretreated for 4 hrs followed by IL3 stimulation and measured after 5 to 60 mins by Western blot analysis	Mus musculus	1	ALA4422612	cell-based format	Scientific Literature