#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4311869	B	Displacement of Europium-labeled angiotensin-2 from human AT1 receptor expressed in CHOK1 cell membranes after 120 mins by DELFIA	Homo sapiens	41	ALA4308919	cell-based format	Scientific Literature
2.	ALA4311870	F	In vivo antagonist activity at AT1 receptor in Sprague-Dawley rat assessed as inhibition of angiotensin-2-induced pressor response at 3 mg/kg, iv treated for 5 mins at 15 mins post 2 doses of angiotensin-2 treatment at 15 minutes apart followed by ANP treatment and subsequent angiotensin-2 re-challenge after 60 mins relative to control	Rattus norvegicus	14	ALA4308919	organism-based format	Scientific Literature
3.	ALA4311871	F	In vivo inhibition of NEP in Sprague-Dawley rat assessed as potentiation of ANP-induced elevation of urinary cGMP level at 3 mg/kg, iv treated for 5 mins at 15 mins post 2 doses of angiotensin-2 treatment at 15 minutes apart followed by ANP treatment measured up to 60 mins by EIA relative to control	Rattus norvegicus	14	ALA4308919	organism-based format	Scientific Literature
4.	ALA4311872	B	Inhibition of NEP (unknown origin) preincubated for 10 mins followed by fluorogenic substrate addition and measured after 20 mins by fluorescence assay	Homo sapiens	41	ALA4308919	single protein format	Scientific Literature
5.	ALA4311873	B	Displacement of Europium-labeled angiotensin-2 from human AT2 receptor expressed in CHOK1 cell membranes after 120 mins by DELFIA	Homo sapiens	3	ALA4308919	cell-based format	Scientific Literature
6.	ALA4311874	B	Inhibition of recombinant human ACE using Mca-BK2 as substrate preincubated for 10 mins followed by fluorogenic substrate addition and measured after 20 mins by fluorescence assay	Homo sapiens	3	ALA4308919	single protein format	Scientific Literature
7.	ALA4311875	B	Inhibition of APP (unknown origin)	Homo sapiens	3	ALA4308919	single protein format	Scientific Literature
8.	ALA4311876	B	Inhibition of recombinant human ECE1	Homo sapiens	3	ALA4308919	single protein format	Scientific Literature
9.	ALA4311877	F	Antihypertensive activity in spontaneously hypertensive rat assessed as reduction in mean arterial pressure administered via oral gavage in ascending cumulative doses every 60 mins measured up to 24 hrs by telemetry method	Rattus norvegicus	3	ALA4308919	organism-based format	Scientific Literature
10.	ALA4311879	F	Antihypertensive activity in DOCA salt-induced CD-1 rat model of hypertension assessed as reduction in blood pressure administered via oral gavage in ascending cumulative doses every 60 mins measured up to 24 hrs by telemetry method	Rattus norvegicus	2	ALA4308919	organism-based format	Scientific Literature
11.	ALA4311880	B	Selectivity ratio of Ki for human AT2 receptor to Ki for human AT1 receptor	Homo sapiens	1	ALA4308919	assay format	Scientific Literature
12.	ALA4311881	B	Selectivity ratio of IC50 for recombinant human ECE1 to IC50 for recombinant human NEP	Homo sapiens	1	ALA4308919	assay format	Scientific Literature
13.	ALA4311882	F	Antagonist activity at AT1 receptor (unknown origin) by inositol phosphate accumulation assay relative to control	Homo sapiens	2	ALA4308919	single protein format	Scientific Literature
14.	ALA4311884	A	Induction of angioedema in normotensive rat assessed as increase in tracheal plasma extravasation by measuring Evans blue dye leakage into peritracheal tissue up to 100 mg/kg, po	Rattus norvegicus	1	ALA4308919	organism-based format	Scientific Literature