| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4372253 | B | Inhibition of recombinant 6His-Tev-tagged LRRK2 (1326 to 2527) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-RLGRDKYKTLRQIRQGNTKQR-OH as substrate preincubated for 30 mins followed by substrate addition and measured after 2 hrs by TR-FRET assay | Homo sapiens | 26 | ALA4371037 | cell-based format | Scientific Literature | |
| 2. | ALA4372254 | P | Lipophilicity, log D of the compound at pH 7.4 by chromatographic method | 26 | ALA4371037 | small-molecule physicochemical format | Scientific Literature | ||
| 3. | ALA4372255 | P | Kinetic solubility of the compound | 26 | ALA4371037 | small-molecule physicochemical format | Scientific Literature | ||
| 4. | ALA4372256 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 20 | ALA4371037 | microsome format | Scientific Literature | |
| 5. | ALA4372257 | A | Ratio of permeability across apical to basolateral side in MDCK2-MDR1 cells transduced with BacMam2-BCRP in presence of P-gp inhibitor GF120918 to absence of GF120918 | Canis lupus familiaris | 15 | ALA4371037 | cell-based format | Scientific Literature | |
| 6. | ALA4372258 | A | Passive permeability across apical to basolateral side in MDCK2-MDR1 cells transduced with BacMam2-BCRP at 3 uM after 90 mins in presence of P-gp inhibitor GF120918 by Transwell assay | Canis lupus familiaris | 15 | ALA4371037 | cell-based format | Scientific Literature |
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