| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4406330 | B | Inhibition of GST-tagged recombinant PI5P4Kalpha (unknown origin) incubated for 1 hr in presence of DPPS and PI5P at 66 uM by ADP-Glo assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA4406331 | B | Binding affinity to recombinant PI5P4Kalpha (unknown origin) assessed as protein-labeling at 10 uM incubated for 2 hrs by mass spectrometry | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 3. | ALA4406332 | B | Binding affinity to recombinant PI5P4Kbeta (unknown origin) assessed as protein-labeling at 10 uM incubated for 2 hrs by mass spectrometry | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 4. | ALA4406333 | B | Inhibition of GST-tagged recombinant PI5P4Kalpha (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assay | Homo sapiens | 24 | single protein format | Scientific Literature | ||
| 5. | ALA4406334 | B | Inhibition of GST-tagged recombinant PI5P4Kbeta (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assay | Homo sapiens | 24 | single protein format | Scientific Literature | ||
| 6. | ALA4406335 | P | Lipophilicity, logD of the compound | 24 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA4406336 | B | Induction of stabilization of PI5P4Kalpha in HEK293T cells at 1 to 15 uM incubated for 1 hr at 40 to 67 degC by Western blot analysis based isothermal CETSA method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA4406337 | B | Induction of stabilization of PI5P4Kbeta in HEK293T cells at 1 to 15 uM incubated for 1 hr at 40 to 67 degC by Western blot analysis based isothermal CETSA method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4406338 | A | Permeability of the compound by PAMPA method | 3 | assay format | Scientific Literature | |||
| 10. | ALA4406339 | A | Stability in rat liver microsomes at 1 uM in presence of NADPH regeneration system incubated for 15 mins by LC-MS analysis | Rattus norvegicus | 4 | microsome format | Scientific Literature | ||
| 11. | ALA4406340 | B | Binding affinity to partial length human ACVR2A expressed in bacterial system at 1 uM by KINOMEscan assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA4406341 | B | Binding affinity to partial length human TGFBR2 expressed in bacterial system at 1 uM by KINOMEscan assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4406345 | B | Inhibition of human ACVR2B expressed in baculovirus expression system | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 14. | ALA4406346 | B | Inhibition of human TGFBR2 expressed in baculovirus expression system | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 15. | ALA4406349 | B | Binding affinity to human PI5P4IKgamma | Homo sapiens | 4 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!