# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4411612 | B | Stabilization of 5'-FAM/3'-TAMRA labelled AR1 G-quadruplex oligonucleotide (unknown origin) assessed as change in melting temperature t1/2 at 1 uM after 16 hrs in presence of 100 mM K+ by FRET assay | Not specified | 9 | ALA4411261 | nucleic acid format | Scientific Literature | |
2. | ALA4411613 | B | Stabilization of 5'-FAM/3'-TAMRA labelled AR3 G-quadruplex oligonucleotide (unknown origin) assessed as change in melting temperature t1/2 at 1 uM after 16 hrs in presence of 100 mM K+ by FRET assay | Not specified | 9 | ALA4411261 | nucleic acid format | Scientific Literature | |
3. | ALA4411614 | B | Stabilization of 5'-FAM/3'-TAMRA labelled CTATAGCGCGCTATAG dsDNA (unknown origin) assessed as change in melting temperature t1/2 at 1 uM after 16 hrs in presence of 100 mM K+ by FRET assay | Not specified | 9 | ALA4411261 | assay format | Scientific Literature | |
4. | ALA4411615 | B | Binding affinity to 5'-Biotinylated-AR1 G-quadruplex oligonucleotide (unknown origin) by SPR analysis | Not specified | 9 | ALA4411261 | nucleic acid format | Scientific Literature | |
5. | ALA4411617 | B | Binding affinity to 5'-Biotinylated-AR1 G-quadruplex oligonucleotide (unknown origin) by SPR analysis relative to control | Not specified | 9 | ALA4411261 | nucleic acid format | Scientific Literature | |
6. | ALA4411618 | A | Cytotoxicity against human PNT1A cells assessed as reduction in cell viability after 48 hrs by MTS assay | Homo sapiens | 9 | ALA4411261 | cell-based format | Scientific Literature | |
7. | ALA4411619 | F | Cytotoxicity against human DU145 cells assessed as reduction in cell viability after 48 hrs by MTS assay | Homo sapiens | 9 | ALA4411261 | cell-based format | Scientific Literature | |
8. | ALA4411620 | F | Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTS assay | Homo sapiens | 9 | ALA4411261 | cell-based format | Scientific Literature | |
9. | ALA4411621 | F | Cytotoxicity against human LNCAP cells expressing androgen receptor T877A point mutant assessed as reduction in cell viability after 48 hrs by MTS assay | Homo sapiens | 9 | ALA4411261 | cell-based format | Scientific Literature | |
10. | ALA4411622 | F | Cytotoxicity against human 22Rv1 cells expressing full length androgen receptor H875Y point mutant assessed as reduction in cell viability after 48 hrs by MTS assay | Homo sapiens | 9 | ALA4411261 | cell-based format | Scientific Literature |