#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4384180	B	Inhibition of human TOPK using MBP as substrate after 2 hrs in presence of [gamma-33P]-ATP by filter-binding method	Homo sapiens	44	ALA4382235	single protein format	Scientific Literature
2.	ALA4384181	F	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	Homo sapiens	44	ALA4382235	cell-based format	Scientific Literature
3.	ALA4384182	F	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	Homo sapiens	44	ALA4382235	cell-based format	Scientific Literature
4.	ALA4384183	F	Antiproliferative activity against human HCT15 cells after 72 hrs by MTT assay	Homo sapiens	44	ALA4382235	cell-based format	Scientific Literature
5.	ALA4384184	B	Inhibition of TOPK autophosphorylation at Thr9 residue in human SW620 cells at 50 to 100 nM after 48 hrs by Western blot analysis	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
6.	ALA4384185	B	Inhibition of TOPK in human SW620 cells assessed as reduction in Histone H3 phosphorylation at Ser10 residue at 50 to 100 nM after 48 hrs by Western blot analysis	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
7.	ALA4384186	B	Inhibition of TOPK in human SW620 cells assessed as reduction in ERK1/2 phosphorylation at at 50 to 100 nM after 48 hrs by Western blot analysis	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
8.	ALA4384187	B	Inhibition of TOPK autophosphorylation at Thr9 residue in human HCT15 cells at 50 to 100 nM after 48 hrs by Western blot analysis	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
9.	ALA4384188	B	Inhibition of TOPK in human HCT15 cells assessed as reduction in Histone H3 phosphorylation at Ser10 residue at 50 to 100 nM after 48 hrs by Western blot analysis	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
10.	ALA4384189	B	Inhibition of TOPK in human HCT15 cells assessed as reduction in ERK1/2 phosphorylation at at 50 to 100 nM after 48 hrs by Western blot analysis	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
11.	ALA4384190	B	Inhibition of TOPK autophosphorylation at Thr9 residue in human HCT116 cells at 50 to 100 nM after 48 hrs by Western blot analysis	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
12.	ALA4384191	B	Inhibition of TOPK in human HCT116 cells assessed as reduction in Histone H3 phosphorylation at Ser10 residue at 50 to 100 nM after 48 hrs by Western blot analysis	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
13.	ALA4384192	B	Inhibition of TOPK in human HCT116 cells assessed as reduction in ERK1/2 phosphorylation at at 50 to 100 nM after 48 hrs by Western blot analysis	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
14.	ALA4384193	B	Inhibition of TOPK autophosphorylation at Thr9 residue in human A549 cells at 50 to 100 nM after 48 hrs by Western blot analysis	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
15.	ALA4384194	B	Inhibition of TOPK in human A549 cells assessed as reduction in Histone H3 phosphorylation at Ser10 residue at 50 to 100 nM after 48 hrs by Western blot analysis	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
16.	ALA4384195	B	Inhibition of TOPK in human A549 cells assessed as reduction in ERK1/2 phosphorylation at at 50 to 100 nM after 48 hrs by Western blot analysis	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
17.	ALA4384196	F	Antiproliferative activity against human HCT116 cells by MTT assay	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
18.	ALA4384197	F	Antiproliferative activity against human HCT15 cells by MTT assay	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
19.	ALA4384198	F	Antiproliferative activity against human SW620 cells by MTT assay	Homo sapiens	1	ALA4382235	cell-based format	Scientific Literature
20.	ALA4384199	F	Antitumor activity against human HCT116 cells xenografted in nude mouse assessed as tumor growth inhibition at 10 mg/kg, po qd administered via gavage for 3 weeks and measured every 3 days relative to control	Homo sapiens	1	ALA4382235	organism-based format	Scientific Literature