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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4383162 | Binding | Binding affinity to Pseudomonas aeruginosa PAO1 NB52019 LpxC after 60 to 420 secs by SPR method | Pseudomonas aeruginosa PAO1 | 16 | ALA4382199 | single protein format | Scientific Literature | |
2. | ALA4383163 | Functional | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after 20 hrs by CLSI protocol-based microdilution assay | Pseudomonas aeruginosa | 16 | ALA4382199 | organism-based format | Scientific Literature | |
3. | ALA4383164 | Functional | Antimicrobial activity against Escherichia coli ATCC 25922 after 20 hrs by CLSI protocol-based microdilution assay | Escherichia coli | 16 | ALA4382199 | organism-based format | Scientific Literature | |
4. | ALA4383165 | Functional | Antimicrobial activity against Klebsiella pneumoniae ATCC 43816 after 20 hrs by CLSI protocol-based microdilution assay | Klebsiella pneumoniae | 18 | ALA4382199 | organism-based format | Scientific Literature | |
5. | ALA4383166 | Physicochemical | Lipophilicity, log D of the compound at pH 7.4 | 15 | ALA4382199 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4383167 | ADME | Protein binding in mouse plasma | Mus musculus | 1 | ALA4382199 | cell-free format | Scientific Literature | |
7. | ALA4383168 | ADME | Protein binding in rat plasma | Rattus norvegicus | 1 | ALA4382199 | cell-free format | Scientific Literature | |
8. | ALA4383169 | ADME | Protein binding in dog plasma | Canis lupus familiaris | 1 | ALA4382199 | cell-free format | Scientific Literature | |
9. | ALA4383170 | ADME | Protein binding in human plasma | Homo sapiens | 1 | ALA4382199 | cell-free format | Scientific Literature | |
10. | ALA4383171 | Physicochemical | Solubility of the compound at pH 7.4 | 1 | ALA4382199 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4383172 | Physicochemical | Solubility of the compound at pH 9 | 1 | ALA4382199 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA4383173 | ADME | Clearance in mouse at 60 mg/kg, iv | Mus musculus | 1 | ALA4382199 | organism-based format | Scientific Literature | |
13. | ALA4383174 | ADME | Volume of distribution at steady state in mouse at 60 mg/kg, iv | Mus musculus | 1 | ALA4382199 | organism-based format | Scientific Literature | |
14. | ALA4383175 | ADME | Half life in mouse at 60 mg/kg, iv | Mus musculus | 1 | ALA4382199 | organism-based format | Scientific Literature | |
15. | ALA4383176 | ADME | Clearance in rat at 5 mg/kg, iv | Rattus norvegicus | 1 | ALA4382199 | organism-based format | Scientific Literature | |
16. | ALA4383177 | ADME | Volume of distribution at steady state in rat at 5 mg/kg, iv | Rattus norvegicus | 1 | ALA4382199 | organism-based format | Scientific Literature | |
17. | ALA4383178 | ADME | Half life in rat at 5 mg/kg, iv | Rattus norvegicus | 1 | ALA4382199 | organism-based format | Scientific Literature | |
18. | ALA4383179 | ADME | Clearance in dog at 10 mg/kg, iv | Canis lupus familiaris | 1 | ALA4382199 | organism-based format | Scientific Literature | |
19. | ALA4383180 | ADME | Volume of distribution at steady state in dog at 10 mg/kg, iv | Canis lupus familiaris | 1 | ALA4382199 | organism-based format | Scientific Literature | |
20. | ALA4383181 | ADME | Half life in dog at 10 mg/kg, iv | Canis lupus familiaris | 1 | ALA4382199 | organism-based format | Scientific Literature |