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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4372846 | Binding | Induction of GFP-tagged Fzd1 (unknown origin) internalization expressed in human U2OS cells at 12.5 after 6 hrs by confocal microscopic method relative to control | Homo sapiens | 9 | ALA4371061 | cell-based format | Scientific Literature | |
2. | ALA4372847 | Binding | Inhibition of Wnt3A-stimulated Wnt/beta-catenin pathway in HEK293 cells transfected with p8xTOPFlash, Renilla luciferase plasmid pRL-TK and pLKO.1 after 8 hrs by Dual topflash luciferase reporter gene assay | Homo sapiens | 6 | ALA4371061 | cell-based format | Scientific Literature | |
3. | ALA4372861 | Binding | Inhibition of Wnt/beta-catenin signaling pathway in human HCT116 cells cytosol lysate harboring beta-catenin mutation assessed as reduction in Axin2 protein expression at 5 to 10 uM after 18 hrs by Western blot analysis | Homo sapiens | 1 | ALA4371061 | subcellular format | Scientific Literature | |
4. | ALA4372862 | Binding | Inhibition of Wnt/beta-catenin signaling pathway in human HCT116 cells cytosol lysate harboring beta-catenin mutation assessed as reduction in beta-catenin protein expression at 5 to 10 uM after 18 hrs by Western blot analysis | Homo sapiens | 1 | ALA4371061 | subcellular format | Scientific Literature | |
5. | ALA4372863 | Binding | Inhibition of Wnt/beta-catenin signaling pathway in human HCT116 whole cell lysate harboring beta-catenin mutation assessed as reduction in c-Myc protein expression at 5 to 10 uM after 18 hrs by Western blot analysis | Homo sapiens | 1 | ALA4371061 | subcellular format | Scientific Literature | |
6. | ALA4372864 | Binding | Inhibition of Wnt/beta-catenin signaling pathway in human HCT116 whole cell lysate harboring beta-catenin mutation assessed as reduction in survivin protein expression at 5 to 10 uM after 18 hrs by Western blot analysis | Homo sapiens | 1 | ALA4371061 | subcellular format | Scientific Literature | |
7. | ALA4372865 | Binding | Inhibition of Wnt/beta-catenin signaling pathway in human HCT116 whole cell lysate harboring cyclin D1 mutation assessed as reduction in survivin protein expression at 5 to 10 uM after 18 hrs by Western blot analysis | Homo sapiens | 1 | ALA4371061 | subcellular format | Scientific Literature |