# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4307473 | B | Inhibition of biotinylated recombinant human C-terminal FC/Avi-tagged PDL1 (19 to 239 residues) and PD1 (unknown origin) interaction at 0.03 to 30 uM by SPR analysis | Homo sapiens | 4 | ALA4304794 | protein complex format | Scientific Literature | |
2. | ALA4307474 | B | Inhibition of biotinylated recombinant human C-terminal FC -tagged PD1 (25 to 167 residues) and PDL1 (unknown origin) interaction at 0.3 to 30 uM by SPR analysis | Homo sapiens | 4 | ALA4304794 | protein complex format | Scientific Literature | |
3. | ALA4307475 | B | Inhibition of PD1/PDL1 (unknown origin) interaction by ELISA | Homo sapiens | 2 | ALA4304794 | protein complex format | Scientific Literature | |
4. | ALA4307476 | B | Inhibition of PDL1 in human MDA-MB-21 cells assessed as recovery of mouse splenocyte proliferation at 100 nM by CFSE-based FACS analysis relative to control | Homo sapiens | 1 | ALA4304794 | cell-based format | Scientific Literature | |
5. | ALA4307479 | B | Binding affinity to biotinylated recombinant human C-terminal FC/Avi-tagged PDL1 (19 to 239 residues) at 0.03 to 30 uM by SPR analysis | Homo sapiens | 4 | ALA4304794 | single protein format | Scientific Literature | |
6. | ALA4307480 | B | Binding affinity to biotinylated recombinant human C-terminal FC -tagged PD1 (25 to 167 residues) at 0.3 to 30 uM by SPR analysis | Homo sapiens | 3 | ALA4304794 | single protein format | Scientific Literature | |
7. | ALA4330221 | B | Inhibition of mouse PDL1 in mouse splenocytes assessed as rescue of splenocyte effector function | Mus musculus | 1 | ALA4330055 | cell-based format | Scientific Literature | |
8. | ALA4330222 | B | Inhibition of mouse PDL2 in mouse splenocytes assessed as rescue of splenocyte effector function | Mus musculus | 1 | ALA4330055 | cell-based format | Scientific Literature | |
9. | ALA4613350 | F | Antitumor activity against mouse CT26 cells xenografted in mouse assessed as reduction in tumor growth at 3 mg/kg after 25 days relative to control | Mus musculus | 1 | ALA4613205 | organism-based format | Scientific Literature | |
10. | ALA4613351 | B | Inhibition of PDL1 (unknown origin) | Homo sapiens | 3 | ALA4613205 | single protein format | Scientific Literature | |
11. | ALA4613352 | B | Inhibition of PDL2 (unknown origin) | Homo sapiens | 1 | ALA4613205 | single protein format | Scientific Literature | |
12. | ALA4613353 | F | Antiproliferative activity against mouse splenocytes at 100 nM relative to control | Mus musculus | 4 | ALA4613205 | cell-based format | Scientific Literature |