| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4404018 | B | Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated for 30 mins by TR-FRET assay | Homo sapiens | 27 | single protein format | Scientific Literature | ||
| 2. | ALA4404019 | P | Lipophilicity, log D of the compound at pH 7.4 by chromatographic method | 7 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4404020 | F | Inhibition of LPS-induced IL6 production in human whole blood preincubated for 30 mins followed by LPS addition measured after 18 to 24 hrs | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 4. | ALA4404021 | F | Inhibition of LPS-induced MCP1 production in human whole blood preincubated for 30 mins followed by LPS addition measured after 18 to 24 hrs | Homo sapiens | 3 | tissue-based format | Scientific Literature | ||
| 5. | ALA4404022 | B | Inhibition of BAZ2A (unknown origin) by TR-FRET assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 6. | ALA4404024 | A | Metabolic stability in rat liver microsomes | Rattus norvegicus | 4 | microsome format | Scientific Literature | ||
| 7. | ALA4404025 | A | Stability in rat hepatocytes | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4404026 | A | Fraction unbound in rat plasma at 1 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA4404027 | A | Unbound clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA4404028 | A | Clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA4404029 | A | Volume of distribution at steady state in rat at 1 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA4404030 | A | Half life in rat at 1 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA4404031 | A | Metabolic stability in dog liver microsomes | Canis lupus familiaris | 3 | microsome format | Scientific Literature | ||
| 14. | ALA4404032 | A | Stability in dog hepatocytes | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4404033 | A | Fraction unbound in dog plasma at 0.5 mg/kg, iv | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 16. | ALA4404034 | A | Clearance in dog at 0.5 mg/kg, iv | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 17. | ALA4404035 | A | Unbound clearance in dog at 0.5 mg/kg, iv | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 18. | ALA4404036 | A | Volume of distribution at steady state in dog at 0.5 mg/kg, iv | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 19. | ALA4404037 | A | Half life in dog at 0.5 mg/kg, iv | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 20. | ALA4404038 | A | Oral bioavailability in dog at 1 mg/kg | Canis lupus familiaris | 3 | organism-based format | Scientific Literature |
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