# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4357330 | A | Metabolic stability in cynomolgus monkey liver microsomes assessed as half life | Macaca fascicularis | 6 | ALA4354834 | microsome format | Scientific Literature | |
2. | ALA4357331 | A | Metabolic stability in dog liver microsomes assessed as half life | Canis lupus familiaris | 6 | ALA4354834 | microsome format | Scientific Literature | |
3. | ALA4357332 | B | Inhibition of human activated factor XI using pyro-Glu-Pro-Arg-pNA as substrate by spectrophotometry | Homo sapiens | 17 | ALA4354834 | single protein format | Scientific Literature | |
4. | ALA4357333 | F | Anticoagulant activity in human plasma assessed as concentration required to increase activated partial thromboplastin time by anticoagulant auto-analyser | Homo sapiens | 17 | ALA4354834 | cell-free format | Scientific Literature | |
5. | ALA4357334 | A | Metabolic stability in human liver microsomes assessed as half life | Homo sapiens | 17 | ALA4354834 | microsome format | Scientific Literature | |
6. | ALA4357335 | A | Permeability of the compound across apical side to basolateral side in human Caco2 cells | Homo sapiens | 17 | ALA4354834 | cell-based format | Scientific Literature | |
7. | ALA4357336 | A | Permeability of the compound across basolateral side to apical side in human Caco2 cells | Homo sapiens | 17 | ALA4354834 | cell-based format | Scientific Literature | |
8. | ALA4357337 | A | Efflux ratio of permeability from basolateral to apical over apical to basolateral side in human Caco2 cells | Homo sapiens | 11 | ALA4354834 | cell-based format | Scientific Literature | |
9. | ALA4357338 | A | Metabolic stability in rat liver microsomes assessed as half life | Rattus norvegicus | 9 | ALA4354834 | microsome format | Scientific Literature | |
10. | ALA4357390 | B | Inhibition of rabbit activated His-tagged factor XI expressed in Escherichia coli using pyro-Glu-Pro-Arg-pNA as substrate by spectrophotometry | Oryctolagus cuniculus | 3 | ALA4354834 | assay format | Scientific Literature | |
11. | ALA4357391 | F | Anticoagulant activity in rabbit plasma assessed as concentration required to increase prothrombin time incubated for 1 min followed by aPTT reagent addition and measured after 3 mins by anticoagulant auto-analyser | Oryctolagus cuniculus | 3 | ALA4354834 | cell-free format | Scientific Literature | |
12. | ALA4357392 | B | Inhibition of activated human coagulation factor VII using H-(D)-Ile-Pro-Arg-pNA as substrate by spectrophotometry | Homo sapiens | 1 | ALA4354834 | single protein format | Scientific Literature | |
13. | ALA4357393 | B | Inhibition of activated human coagulation factor IX using 7-amino-4-methylcoumarin as substrate by spectrofluorimetry | Homo sapiens | 1 | ALA4354834 | single protein format | Scientific Literature | |
14. | ALA4357394 | B | Inhibition of activated human coagulation factor X using N-benzoyl-Ile-Glu-OH-OMe-Gly-Arg-pNA as substrate by spectrophotometry | Homo sapiens | 1 | ALA4354834 | single protein format | Scientific Literature | |
15. | ALA4357395 | B | Inhibition of activated human coagulation factor XII using H-(D)-CHT-Gly-Arg-pNA as substrate by spectrophotometry | Homo sapiens | 1 | ALA4354834 | single protein format | Scientific Literature | |
16. | ALA4357396 | B | Inhibition of human alpha-thrombin using pyro-Glu-Pro-Arg-pNA as substrate by spectrophotometry | Homo sapiens | 1 | ALA4354834 | single protein format | Scientific Literature | |
17. | ALA4357397 | B | Inhibition of human trypsin using N-benzoyl-Ile-Glu-OH-OMe-Gly-Arg-pNA as substrate by spectrophotometry | Homo sapiens | 1 | ALA4354834 | protein format | Scientific Literature | |
18. | ALA4357398 | B | Inhibition of human kallikrein using H-(D)-Pro-Phe-Arg-pNA as substrate by spectrophotometry | Homo sapiens | 1 | ALA4354834 | single protein format | Scientific Literature | |
19. | ALA4357399 | B | Inhibition of activated human protein C using pyro-Glu-Pro-Arg-pNA as substrate by spectrophotometry | Homo sapiens | 1 | ALA4354834 | single protein format | Scientific Literature | |
20. | ALA4357400 | B | Inhibition of human plasmin using H-(D)-Val-Leu-Lys-pNA as substrate by spectrophotometry | Homo sapiens | 1 | ALA4354834 | single protein format | Scientific Literature |