# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4334319 | P | Solubility of the compound in pH 6.5 solution | 4 | ALA4330182 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA4334321 | F | Cytotoxicity against human MALME-3M cells after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4330182 | cell-based format | Scientific Literature | |
3. | ALA4334322 | F | Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4330182 | cell-based format | Scientific Literature | |
4. | ALA4334323 | F | Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4330182 | cell-based format | Scientific Literature | |
5. | ALA4334324 | B | Binding affinity to calf thymus DNA at 60 uM by fluorescence spectral analysis | Bos taurus | 2 | ALA4330182 | nucleic acid format | Scientific Literature | |
6. | ALA4334330 | F | Induction of DCD mRNA expression in human MALME-3M cells at 30 to 100 nM after 24 hrs by RT-qPCR method | Homo sapiens | 3 | ALA4330182 | cell-based format | Scientific Literature | |
7. | ALA4334331 | F | Induction of DCD mRNA expression in human SK-MEL-28 cells at 30 to 100 nM after 24 hrs by RT-qPCR method | Homo sapiens | 3 | ALA4330182 | cell-based format | Scientific Literature | |
8. | ALA4334332 | F | Induction of DCD mRNA expression in human HCT116 cells at 1 to 10 uM after 24 hrs by RT-qPCR method | Homo sapiens | 3 | ALA4330182 | cell-based format | Scientific Literature | |
9. | ALA4420983 | F | Cytotoxicity in human HCT116 cells assessed as induction of cell death at 0.3 to 30 uM incubated for 24 to 48 hrs by trypan blue dye exclusion assay | Homo sapiens | 1 | ALA4420075 | cell-based format | Patent Bioactivity Data | |
10. | ALA4420984 | F | Induction of autophagy in human HCT116 cells assessed as increase in of LC3A-II level incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4420075 | cell-based format | Patent Bioactivity Data | |
11. | ALA4420985 | F | Induction of autophagy in human HCT116 cells assessed as increase in of LC3B-II level incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4420075 | cell-based format | Patent Bioactivity Data | |
12. | ALA4420988 | F | Induction of DNA fragmentation in human HCT116 cells at 0.3 to 30 uM incubated for 24 hrs by FACS analysis | Homo sapiens | 1 | ALA4420075 | cell-based format | Patent Bioactivity Data | |
13. | ALA4420989 | F | Induction of cell cycle arrest in human HCT116 cells assessed as accumulation at S phase at 0.3 to 30 uM incubated for 18 to 24 hrs by propidium iodide staining based assay | Homo sapiens | 1 | ALA4420075 | cell-based format | Patent Bioactivity Data | |
14. | ALA4420990 | A | Drug accumulation in human HCT116 cells assessed as sub-cellular localization at 5 uM incubated for 1 hr by DAPI staining based | Homo sapiens | 1 | ALA4420075 | cell-based format | Patent Bioactivity Data | |
15. | ALA4420991 | A | Drug accumulation in human PC3M cells assessed as sub-cellular localization at 30 uM incubated for 1 hr by DAPI staining based | Homo sapiens | 1 | ALA4420075 | cell-based format | Patent Bioactivity Data | |
16. | ALA4420992 | A | Drug accumulation in human SF295 cells assessed as sub-cellular localization at 30 uM incubated for 1 hr by DAPI staining based | Homo sapiens | 1 | ALA4420075 | cell-based format | Patent Bioactivity Data | |
17. | ALA4420993 | A | Drug accumulation in human HCT8 cells assessed as sub-cellular localization at 30 uM incubated for 1 hr by DAPI staining based | Homo sapiens | 1 | ALA4420075 | cell-based format | Patent Bioactivity Data | |
18. | ALA4420994 | A | Drug accumulation in human MALME-3M cells assessed as sub-cellular localization at 30 uM incubated for 1 hr by DAPI staining based | Homo sapiens | 1 | ALA4420075 | cell-based format | Patent Bioactivity Data | |
19. | ALA4420995 | A | Drug accumulation in human PC3 cells assessed as sub-cellular localization in endoplasmic reticulum at 30 uM incubated for 1 hr by time course imaging assay | Homo sapiens | 1 | ALA4420075 | subcellular format | Patent Bioactivity Data | |
20. | ALA4420996 | F | Induction of auto-phagocytosis in human PC3 cells at 30 uM incubated for 1 hr by time course imaging assay | Homo sapiens | 1 | ALA4420075 | cell-based format | Patent Bioactivity Data |