# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4431204 | B | Displacement of [3H]MLA from human alpha7 nAChR transfected in human SH-SY5Y cell membranes after 120 mins by liquid scintillation counting | Homo sapiens | 21 | ALA4428135 | cell-based format | Scientific Literature | |
2. | ALA4431205 | B | Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK293 cell membranes after 120 mins by liquid scintillation counting | Homo sapiens | 21 | ALA4428135 | cell-based format | Scientific Literature | |
3. | ALA4431206 | B | Displacement of [3H]epibatidine from human alpha4beta2 nAChR transfected in HEK293 cell membranes after 120 mins by liquid scintillation counting | Homo sapiens | 21 | ALA4428135 | cell-based format | Scientific Literature | |
4. | ALA4431209 | B | Selectivity index, reciprocal of ratio of Ki for human alpha3beta4 nAChR transfected in HEK293 cells to Ki for human alpha4beta2 nAChR transfected in HEK293 cells | Homo sapiens | 21 | ALA4428135 | cell-based format | Scientific Literature | |
5. | ALA4431223 | B | Displacement of [125I]alpha-bungarotoxin from human N-muscle type nAChR alpha1 expressed in human RD cells at 1 uM | Homo sapiens | 4 | ALA4428135 | cell-based format | Scientific Literature | |
6. | ALA4431224 | B | Displacement of [3H]BRL-43694 from human recombinant 5-HT3 receptor expressed in CHO cells at 100 nM | Homo sapiens | 4 | ALA4428135 | cell-based format | Scientific Literature | |
7. | ALA4431225 | B | Agonist activity at human alpha7 nAChR expressed in human SH-SY5Y cells assessed as increase in intracellular calcium levels at 10 uM | Homo sapiens | 4 | ALA4428135 | cell-based format | Scientific Literature | |
8. | ALA4431227 | B | Antagonist activity at human alpha3beta4 nAChR expressed in HEK293 cells assessed as rediution in epibatidine-induced intracellular calcium levels at 10 uM | Homo sapiens | 2 | ALA4428135 | cell-based format | Scientific Literature |