# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4424220 | B | Activation of human Nav1.1 expressed in T-Rex-CHO cells assessed as change in decay time constant of channel currents at 3 uM at holding potential of -120 mV by automated patch-clamp electrophysiology assay relative to control | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
2. | ALA4424221 | B | Activation of human Nav1.1 expressed in T-Rex-CHO cells assessed as change in decay time constant of channel currents at 10 uM at holding potential of -120 mV by automated patch-clamp electrophysiology assay relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
3. | ALA4424222 | B | Activation of human Nav1.1 expressed in T-Rex-CHO cells assessed as change in decay time constant of channel currents at 30 uM at holding potential of -120 mV by automated patch-clamp electrophysiology assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA4424223 | B | Activation of human Nav1.1 expressed in T-Rex-CHO cells assessed as change in decay time constant of channel currents at 1 uM by Q-patch assay relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
5. | ALA4424224 | B | Activation of human Nav1.1 expressed in T-Rex-CHO cells assessed as change in decay time constant of channel currents at 3 uM by Q-patch assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA4424225 | B | Activation of human Nav1.1 expressed in T-Rex-CHO cells assessed as change in decay time constant of channel currents at 10 uM by Q-patch assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA4424226 | P | 1-octanol/water partition co-efficient, log D of the compound at pH 7.4 by by chromatographic analysis | 2 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA4424227 | P | Aqueous solubility of compound at pH 6.8 by UV absorbance method | 2 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA4424229 | B | Activation of human Nav1.1 expressed in T-Rex-CHO cells assessed as change in top peak current at 1 uM by Q-patch assay relative to control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
10. | ALA4424247 | B | Activation of human Nav1.1 expressed in T-Rex-CHO cells assessed as change in top peak current at 3 uM by Q-patch assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA4424248 | B | Activation of human Nav1.1 expressed in T-Rex-CHO cells assessed as change in top peak current at 10 uM by Q-patch assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature |