# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4315017 | B | Inhibition of human NPP1 expressed in COS7 cell membranes at 100 uM using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition and measured after 15 mins | Homo sapiens | 2 | ALA4311993 | cell-based format | Scientific Literature | |
2. | ALA4315018 | B | Inhibition of human NPP3 expressed in COS7 cell membranes at 100 uM using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition and measured after 15 mins | Homo sapiens | 4 | ALA4311993 | cell-based format | Scientific Literature | |
3. | ALA4315019 | B | Inhibition of human NTPdase-1 expressed in COS7 cell membranes at 100 uM using ATP as substrate preincubated for 3 mins followed by susbtrate addition and measured after 10 mins by malachite green dye based method | Homo sapiens | 6 | ALA4311993 | cell-based format | Scientific Literature | |
4. | ALA4315020 | B | Inhibition of human NTPdase-2 expressed in COS7 cell membranes at 100 uM using ATP as substrate preincubated for 3 mins followed by susbtrate addition and measured after 10 mins by malachite green dye based method | Homo sapiens | 6 | ALA4311993 | cell-based format | Scientific Literature | |
5. | ALA4315021 | B | Inhibition of human NTPdase-3 expressed in COS7 cell membranes at 100 uM using ATP as substrate preincubated for 3 mins followed by susbtrate addition and measured after 10 mins by malachite green dye based method | Homo sapiens | 6 | ALA4311993 | cell-based format | Scientific Literature | |
6. | ALA4315022 | B | Inhibition of human NTPdase-8 expressed in COS7 cell membranes at 100 uM using ATP as substrate preincubated for 3 mins followed by susbtrate addition and measured after 10 mins by malachite green dye based method | Homo sapiens | 6 | ALA4311993 | cell-based format | Scientific Literature | |
7. | ALA4315027 | F | Agonist activity at human P2Y2 receptor expressed in AD293 cells assessed as inositol-1-phosphate accumulation at 100 uM | Homo sapiens | 7 | ALA4311993 | cell-based format | Scientific Literature | |
8. | ALA4315028 | F | Antagonist activity at human P2Y2 receptor expressed in AD293 cells assessed as inhibition of UTP-induced inositol-1-phosphate accumulation at 100 uM | Homo sapiens | 7 | ALA4311993 | cell-based format | Scientific Literature | |
9. | ALA4315029 | F | Agonist activity at human P2Y2 receptor expressed in AD293 cells assessed as induction of IP1 accumulation at 0.1 to 1 uM | Homo sapiens | 3 | ALA4311993 | cell-based format | Scientific Literature | |
10. | ALA4315030 | F | Agonist activity at human P2Y4 receptor expressed in AD293 cells assessed as inositol-1-phosphate accumulation at 0.1 to 100 uM | Homo sapiens | 8 | ALA4311993 | cell-based format | Scientific Literature | |
11. | ALA4315031 | F | Antagonist activity at human P2Y4 receptor expressed in AD293 cells assessed as inhibition of UTP-induced inositol-1-phosphate accumulation at 0.1 to 100 uM | Homo sapiens | 8 | ALA4311993 | cell-based format | Scientific Literature | |
12. | ALA4315032 | F | Antagonist activity at human P2Y6 receptor expressed in AD293 cells assessed as inhibition of UDP-induced inositol-1-phosphate accumulation at 0.1 to 100 uM | Homo sapiens | 8 | ALA4311993 | cell-based format | Scientific Literature |