#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4352728	B	Inhibition of Plasmodium falciparum N-terminal His6-tagged falcipain-2 (35 residues) expressed in Escherichia coli M15 pREP4 using Z-Lue-Arg-AMC as substrate measured after 30 mins by spectrofluorometric method	Plasmodium falciparum	20		assay format	Scientific Literature
2.	ALA4352729	B	Inhibition of Plasmodium falciparum N-terminal His-tagged falcipain-3 (33 residues) expressed in Escherichia coli M15 pREP4 using Z-Leu-Arg-AMC as substrate measured after 30 mins by spectrofluorometric method	Plasmodium falciparum	20		assay format	Scientific Literature
3.	ALA4352730	F	Antimalarial activity against synchronized ring stage CQ-sensitive Plasmodium falciparum 3D7 infected in human erythrocytes incubated for 24 hrs followed by compound washout and subsequent compound addition and measured after 48 hrs by YOYO-1 probe-based flow cytometry	Plasmodium falciparum	20		organism-based format	Scientific Literature
4.	ALA4352731	F	Antimalarial activity against synchronized ring stage CQ-resistant Plasmodium falciparum W2 infected in human erythrocytes incubated for 24 hrs followed by compound washout and subsequent compound addition and measured after 48 hrs by YOYO-1 probe-based flow cytometry	Plasmodium falciparum	20		organism-based format	Scientific Literature
5.	ALA4352732	A	Half life in Swiss mouse plasma at 1 ug/ml by UPLC-MS analysis	Mus musculus	6		cell-free format	Scientific Literature
6.	ALA4352733	A	Half life in Swiss mouse blood at 1 ug/ml by UPLC-MS analysis	Mus musculus	6		tissue-based format	Scientific Literature
7.	ALA4352734	F	Induction of morphological changes in synchronized ring stage Plasmodium falciparum W2 infected in human erythrocytes assessed as swollen food vacuoles with accumulated hemoglobin at 300 nM measured after 36 hrs by Giemsa staining-based photomicrographic method	Plasmodium falciparum	3		organism-based format	Scientific Literature
8.	ALA4352735	A	Cytotoxicity against HEK293 cells assessed as reduction in cell viability at 25 uM measured after 18 hrs by alamar blue assay	Homo sapiens	6		cell-based format	Scientific Literature
9.	ALA4352737	A	Drug metabolism in human liver microsomes assessed as N,N-bis-demethylation at 10 uM measured after 60 mins in presence of NADPH-generating system by UPLC-MS analysis	Homo sapiens	3		microsome format	Scientific Literature
10.	ALA4352739	A	Drug metabolism in mouse liver microsomes assessed as N,N-bis-demethylation at 10 uM measured after 60 mins in presence of NADPH-generating system by UPLC-MS analysis	Mus musculus	3		microsome format	Scientific Literature
11.	ALA4352740	A	Drug metabolism in human liver microsomes assessed as GSH-adduct formation at 10 uM measured after 60 mins in presence of NADPH-generating system/GSH-EE by UPLC-MS analysis	Homo sapiens	6		microsome format	Scientific Literature
12.	ALA4352741	A	Drug metabolism in mouse liver microsomes assessed as GSH-adduct formation at 10 uM measured after 60 mins in presence of NADPH-generating system/GSH-EE by UPLC-MS analysis	Mus musculus	6		microsome format	Scientific Literature
13.	ALA4352742	A	Intrinsic clearance in mouse liver microsomes assessed per mg protein at 1 uM measured after 60 mins in presence of NADPH-generating system by UPLC-MS analysis	Mus musculus	1		microsome format	Scientific Literature
14.	ALA4352745	F	Antimalarial activity against Plasmodium berghei ANKA infected in specific pathogen-free C57BL/6 mouse assessed as reduction in parasitemia at 6.5 to 12.5 mg/kg, ip administered at 72 hrs post-infection and measured daily up to 35 days post-infection by rapid staining-based microscopic analysis	Plasmodium berghei	1		organism-based format	Scientific Literature
15.	ALA4352746	F	Antimalarial activity against Plasmodium berghei ANKA infected in specific pathogen-free C57BL/6 mouse assessed as mouse survival at 6.5 to 12.5 mg/kg, ip administered at 72 hrs post-infection by rapid staining-based microscopic analysis	Plasmodium berghei	1		organism-based format	Scientific Literature
16.	ALA4352747	F	Antimalarial activity against Plasmodium berghei ANKA infected in specific pathogen-free C57BL/6 mouse assessed as reduction in parasitemia at 50 mg/kg, ip administered once daily for 4 days measured up to 35 days post-infection by rapid staining-based microscopic analysis	Plasmodium berghei	2		organism-based format	Scientific Literature
17.	ALA4352748	F	Antimalarial activity against Plasmodium berghei ANKA infected in specific pathogen-free C57BL/6 mouse assessed as reduction in parasitemia at 100 mg/kg, po administered once daily for 4 days measured up to 35 days post-infection by rapid staining-based microscopic analysis	Plasmodium berghei	2		organism-based format	Scientific Literature
18.	ALA4352749	F	Antimalarial activity against Plasmodium berghei ANKA infected in specific pathogen-free C57BL/6 mouse assessed as reduction in disease severity at 100 mg/kg, po administered once daily for 4 days measured up to 35 days post-infection by rapid staining-based microscopic analysis	Plasmodium berghei	2		organism-based format	Scientific Literature