| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4323194 | F | Antiproliferative activity against human RS4:11 cells expressing wild type p53 assessed as cell growth inhibition after 4 days by WST-8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA4323198 | F | Antiproliferative activity against human RS4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as cell growth inhibition after 4 days by WST-8 assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 3. | ALA4323255 | B | Protac activity at GSPT1/CUL4/DDB1/CRBN in human RS4:11 cells expressing wild type p53 assessed as decrease in GSPT1 protein level after 2 hrs by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 4. | ALA4323256 | B | Protac activity at GSPT1/CUL4/DDB1/CRBN in human RS4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as decrease in GSPT1 protein level after 2 hrs by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 5. | ALA4323257 | B | Induction of GSPT1 degradation in human RS4:11 cells measured after 24 hrs by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature |
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