#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4433171	Binding	Inhibition of D5D in Sprague-Dawley rat liver microsomes using [14C]DGLA as substrate preincubated for 5 mins measured after 120 mins	Rattus norvegicus	2	ALA4431397	microsome format	Scientific Literature
2.	ALA4433172	Binding	Inhibition of D6D in Sprague-Dawley rat liver microsomes using [14C]LA as substrate preincubated for 5 mins measured after 30 mins	Rattus norvegicus	2	ALA4431397	microsome format	Scientific Literature
3.	ALA4433173	Binding	Inhibition of SCD in Sprague-Dawley rat liver microsomes using [14C]stearoyl-CoA as substrate preincubated for 5 mins measured after 30 mins	Rattus norvegicus	2	ALA4431397	microsome format	Scientific Literature
4.	ALA4433174	Binding	Inhibition of D5D in human HepG2 cells using [14C]DGLA as substrate preincubated for 30 mins followed by substrate addition measured after 3 hrs	Homo sapiens	2	ALA4431397	cell-based format	Scientific Literature
5.	ALA4433175	Binding	Inhibition of D5D in rat RLN10 cells using [14C]DGLA as substrate preincubated for 30 mins followed by substrate addition measured after 3 hrs	Rattus norvegicus	2	ALA4431397	cell-based format	Scientific Literature
6.	ALA4433176	Binding	Binding affinity to D5D in Sprague-Dawley rat liver microsomes after 150 mins by liquid scintillation counting	Rattus norvegicus	1	ALA4431397	microsome format	Scientific Literature
7.	ALA4433177	Binding	Binding affinity to D5D in Sprague-Dawley rat liver microsomes at 1.2 to 20 nM measured up to 2.5 hrs by liquid scintillation counting	Rattus norvegicus	1	ALA4431397	microsome format	Scientific Literature
8.	ALA4433179	Binding	Reversible binding affinity to D5D in Sprague-Dawley rat liver microsomes assessed as compound bound to protein at 6 nM preincubated for 150 mins followed by 2 fold dilution by 10 uM of T-3364366 measured after 21 hrs by liquid scintillation counting relative to control	Rattus norvegicus	1	ALA4431397	microsome format	Scientific Literature
9.	ALA4433180	Binding	Reversible binding affinity to D5D in Sprague-Dawley rat liver microsomes assessed as dissociation half life at 6 nM preincubated for 150 mins followed by 2 fold dilution by 10 uM of T-3364366 by liquid scintillation counting	Rattus norvegicus	1	ALA4431397	microsome format	Scientific Literature
10.	ALA4433181	Binding	Reversible binding affinity to D5D in Sprague-Dawley rat liver microsomes after 150 mins in presence of trichloroacetate by liquid scintillation counting	Rattus norvegicus	1	ALA4431397	microsome format	Scientific Literature
11.	ALA4433183	Binding	Inhibition of D5D in human HepG2 cells using [14C]DGLA as substrate assessed as suppression of [14C]AA production at 10 uM preincubated for 3 hrs followed by compound washout and addition of substrate measured after 4 hrs by liquid scintillation counting	Homo sapiens	1	ALA4431397	cell-based format	Scientific Literature
12.	ALA4433184	ADME	AUC(0 to 8 hrs) in mouse at 0.10 mg/kg, iv administered in cassette mode	Mus musculus	1	ALA4431397	organism-based format	Scientific Literature
13.	ALA4433185	ADME	AUC(0 to 8 hrs) in mouse at 1 mg/kg, po administered in cassette mode	Mus musculus	1	ALA4431397	organism-based format	Scientific Literature
14.	ALA4433186	ADME	Total clearance in mouse at 0.10 mg/kg, iv administered in cassette mode	Mus musculus	1	ALA4431397	organism-based format	Scientific Literature
15.	ALA4433187	ADME	Volume of distribution in steady state in mouse at 0.10 mg/kg, iv administered in cassette mode	Mus musculus	1	ALA4431397	organism-based format	Scientific Literature
16.	ALA4433188	ADME	MRT in mouse at 0.10 mg/kg, iv administered in cassette mode	Mus musculus	1	ALA4431397	organism-based format	Scientific Literature
17.	ALA4433189	ADME	MRT in mouse at 1 mg/kg, po administered in cassette mode	Mus musculus	1	ALA4431397	organism-based format	Scientific Literature
18.	ALA4433190	ADME	Oral bioavailability in mouse at 1 mg/kg administered in cassette mode	Mus musculus	1	ALA4431397	organism-based format	Scientific Literature
19.	ALA4433191	Binding	Binding affinity to recombinant D6Db5 (1 to 100 residues)/D5Ddes (100 to 444 residues) domain swapped mutant (unknown origin) expressed in baculovirus at 5 to 25 nM after 150 mins by liquid scintillation counting	Homo sapiens	1	ALA4431397	assay format	Scientific Literature
20.	ALA4433192	Binding	Binding affinity to recombinant wild type D5D (unknown origin) expressed in baculovirus at 5 to 25 nM after 150 mins by liquid scintillation counting	Homo sapiens	1	ALA4431397	assay format	Scientific Literature