# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4405879 | Binding | Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) in sodium phosphate buffer at pH 7.6 by WaterLOGSY NMR analysis | Homo sapiens | 3 | ALA4402594 | assay format | Scientific Literature | |
2. | ALA4405880 | Binding | Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) assessed as saturation transfer at lipophilic residues at 800 uM in sodium phosphate buffer at pH 7.6 by WaterLOGSY NMR analysis | Homo sapiens | 1 | ALA4402594 | assay format | Scientific Literature | |
3. | ALA4405883 | Physicochemical | Conformational stability in water assessed as helical structural propensity by circular dichroism method | 1 | ALA4402594 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4405884 | Physicochemical | Conformational stability in water assessed as helical structural propensity by 2D NMR-ROESY analysis | 1 | ALA4402594 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4405904 | Binding | Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye-based microscale thermophoresis analysis | Homo sapiens | 15 | ALA4402594 | assay format | Scientific Literature | |
6. | ALA4405906 | Physicochemical | Conformational stability in sodium phosphate buffer assessed as increase in alpha-helicity with theta 222 band formation at 100 uM by circular dichroism method | 1 | ALA4402594 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4405919 | Binding | Binding affinity to rabbit LDH-5 assessed as acid-induced dimerization by measuring fluorescence recovery at 50 uM pH 7.6 by nano differential scanning fluorimetry analysis | Oryctolagus cuniculus | 1 | ALA4402594 | single protein format | Scientific Literature | |
8. | ALA4405924 | ADME | Binding affinity to recombinant full length human His-tagged LDH-1 (1 to 322 residues) expressed in Escherichia coli by WaterLOGSY NMR analysis | Homo sapiens | 2 | ALA4402594 | assay format | Scientific Literature |