# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4378742 | B | Binding affinity to human RIPK1 by kinome scan based method | Homo sapiens | 4 | ALA4376828 | single protein format | Scientific Literature | |
2. | ALA4378754 | B | Binding affinity to human MLKL by kinome scan based method | Homo sapiens | 2 | ALA4376828 | single protein format | Scientific Literature | |
3. | ALA4378755 | B | Binding affinity to human RIPK3 by kinome scan based method | Homo sapiens | 2 | ALA4376828 | single protein format | Scientific Literature | |
4. | ALA4378756 | B | Binding affinity to MLKL (unknown origin) assessed as increase in thermal stabilization at 10 uM incubated for 30 mins by thermal shift dye based qPCR analysis | Homo sapiens | 2 | ALA4376828 | single protein format | Scientific Literature | |
5. | ALA4378757 | B | Binding affinity to RIPK1 (unknown origin) assessed as increase in thermal stabilization at 10 uM incubated for 30 mins by thermal shift dye based qPCR analysis | Homo sapiens | 2 | ALA4376828 | single protein format | Scientific Literature | |
6. | ALA4378758 | F | Anti-neprotic activity in human Jurkat cells FADD defient assessed as reduction in TNFalpha-induced necroptosis preincubated for 30 mins followed by addition of TNFalpha-stimulation and further incubated for over night by Cell Titer Glo assay | Homo sapiens | 2 | ALA4376828 | cell-based format | Scientific Literature |