# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4338666 | Functional | Up regulation of pan-cadherin level in human MDA-MB-231 cells up to 10 uM by Western blot analysis | Homo sapiens | 1 | ALA4334533 | cell-based format | Scientific Literature | |
2. | ALA4338667 | ADME | Cytotoxicity against E6/E7 immortalized human HNME cells assessed as inhibition of cell growth measured after 48 hrs by microplate reader analysis | Homo sapiens | 2 | ALA4334533 | cell-based format | Scientific Literature | |
3. | ALA4338668 | Functional | Growth inhibition in human MDA-MB-231 cells at 10 uM after 48 hrs by MTT assay | Homo sapiens | 2 | ALA4334533 | cell-based format | Scientific Literature | |
4. | ALA4338669 | Functional | Growth inhibition in human MCF7 cells at 10 uM after 48 hrs by MTT assay | Homo sapiens | 2 | ALA4334533 | cell-based format | Scientific Literature | |
5. | ALA4338670 | Functional | Induction of morphological changes in human MDA-MB-231 cells assessed as mesenchymal-epithelial transition at 10 uM by inverted microscopic analysis | Homo sapiens | 2 | ALA4334533 | cell-based format | Scientific Literature | |
6. | ALA4338671 | Functional | Induction of morphological changes in human MDA-MB-468 cells assessed as mesenchymal-epithelial transition at 10 uM by inverted microscopic analysis | Homo sapiens | 2 | ALA4334533 | cell-based format | Scientific Literature | |
7. | ALA4338672 | Functional | Induction of morphological changes in human MCF7 cells assessed as mesenchymal-epithelial transition at 10 uM by inverted microscopic analysis | Homo sapiens | 2 | ALA4334533 | cell-based format | Scientific Literature | |
8. | ALA4338673 | Functional | Antimigratory activity in human MDA-MB-231 cells assessed as wound diameter at 5 uM measured after 24 hrs by microscopic analysis | Homo sapiens | 8 | ALA4334533 | cell-based format | Scientific Literature | |
9. | ALA4338674 | Functional | Antimigratory activity in human MDA-MB-231 cells assessed as wound diameter measured after 24 hrs by microscopic analysis (Rvb = 29.5 +/- 1.95%) | Homo sapiens | 1 | ALA4334533 | cell-based format | Scientific Literature | |
10. | ALA4338675 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 48 hrs by microplate reader analysis | Homo sapiens | 2 | ALA4334533 | cell-based format | Scientific Literature | |
11. | ALA4338676 | Functional | Antiproliferative activity against human MDA-MB-468 cells assessed as inhibition of cell growth measured after 48 hrs by microplate reader analysis | Homo sapiens | 2 | ALA4334533 | cell-based format | Scientific Literature | |
12. | ALA4338677 | Functional | Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 48 hrs by microplate reader analysis | Homo sapiens | 2 | ALA4334533 | cell-based format | Scientific Literature | |
13. | ALA4338678 | Unassigned | Selectivity index, ratio of LD50 for E6/E7 immortalized human HNME cells to IC50 for human MDA-MB-231 cells | Homo sapiens | 2 | ALA4334533 | assay format | Scientific Literature | |
14. | ALA4338679 | Unassigned | Selectivity index, ratio of LD50 for E6/E7 immortalized human HNME cells to IC50 for human MDA-MB-468 cells | Homo sapiens | 2 | ALA4334533 | assay format | Scientific Literature | |
15. | ALA4338680 | Unassigned | Selectivity index, ratio of LD50 for E6/E7 immortalized human HNME cells to IC50 for human MCF7 cells | Homo sapiens | 2 | ALA4334533 | assay format | Scientific Literature | |
16. | ALA4338681 | Functional | Induction of apoptosis in human MDA-MB-468 cells assessed as necrotic cells at 8 uM measured after 48 hrs by AnnexinV/7-AAD staining based flow cytometric analysis (Rvb = 0.51%) | Homo sapiens | 1 | ALA4334533 | cell-based format | Scientific Literature | |
17. | ALA4338682 | Functional | Induction of apoptosis in human MDA-MB-468 cells assessed as viable cells at 8 uM measured after 24 hrs by AnnexinV/7-AAD staining based flow cytometric analysis (Rvb = 94.1%) | Homo sapiens | 1 | ALA4334533 | cell-based format | Scientific Literature | |
18. | ALA4338683 | Functional | Induction of apoptosis in human MDA-MB-468 cells assessed as early apoptotic cells at 8 uM measured after 24 hrs by AnnexinV/7-AAD staining based flow cytometric analysis (Rvb = 3.45%) | Homo sapiens | 1 | ALA4334533 | cell-based format | Scientific Literature | |
19. | ALA4338684 | Functional | Induction of apoptosis in human MDA-MB-468 cells assessed as late apoptotic cells at 8 uM measured after 24 hrs by AnnexinV/7-AAD staining based flow cytometric analysis (Rvb = 1.86%) | Homo sapiens | 1 | ALA4334533 | cell-based format | Scientific Literature | |
20. | ALA4338685 | Functional | Induction of apoptosis in human MDA-MB-468 cells assessed as necrotic cells at 8 uM measured after 24 hrs by AnnexinV/7-AAD staining based flow cytometric analysis (Rvb = 0.62%) | Homo sapiens | 1 | ALA4334533 | cell-based format | Scientific Literature |