| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4338666 | F | Up regulation of pan-cadherin level in human MDA-MB-231 cells up to 10 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4338667 | A | Cytotoxicity against E6/E7 immortalized human HNME cells assessed as inhibition of cell growth measured after 48 hrs by microplate reader analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA4338668 | F | Growth inhibition in human MDA-MB-231 cells at 10 uM after 48 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4338669 | F | Growth inhibition in human MCF7 cells at 10 uM after 48 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4338670 | F | Induction of morphological changes in human MDA-MB-231 cells assessed as mesenchymal-epithelial transition at 10 uM by inverted microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4338671 | F | Induction of morphological changes in human MDA-MB-468 cells assessed as mesenchymal-epithelial transition at 10 uM by inverted microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4338672 | F | Induction of morphological changes in human MCF7 cells assessed as mesenchymal-epithelial transition at 10 uM by inverted microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4338673 | F | Antimigratory activity in human MDA-MB-231 cells assessed as wound diameter at 5 uM measured after 24 hrs by microscopic analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 9. | ALA4338674 | F | Antimigratory activity in human MDA-MB-231 cells assessed as wound diameter measured after 24 hrs by microscopic analysis (Rvb = 29.5 +/- 1.95%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4338675 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 48 hrs by microplate reader analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4338676 | F | Antiproliferative activity against human MDA-MB-468 cells assessed as inhibition of cell growth measured after 48 hrs by microplate reader analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4338677 | F | Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 48 hrs by microplate reader analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4338678 | U | Selectivity index, ratio of LD50 for E6/E7 immortalized human HNME cells to IC50 for human MDA-MB-231 cells | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 14. | ALA4338679 | U | Selectivity index, ratio of LD50 for E6/E7 immortalized human HNME cells to IC50 for human MDA-MB-468 cells | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 15. | ALA4338680 | U | Selectivity index, ratio of LD50 for E6/E7 immortalized human HNME cells to IC50 for human MCF7 cells | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 16. | ALA4338681 | F | Induction of apoptosis in human MDA-MB-468 cells assessed as necrotic cells at 8 uM measured after 48 hrs by AnnexinV/7-AAD staining based flow cytometric analysis (Rvb = 0.51%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4338682 | F | Induction of apoptosis in human MDA-MB-468 cells assessed as viable cells at 8 uM measured after 24 hrs by AnnexinV/7-AAD staining based flow cytometric analysis (Rvb = 94.1%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4338683 | F | Induction of apoptosis in human MDA-MB-468 cells assessed as early apoptotic cells at 8 uM measured after 24 hrs by AnnexinV/7-AAD staining based flow cytometric analysis (Rvb = 3.45%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4338684 | F | Induction of apoptosis in human MDA-MB-468 cells assessed as late apoptotic cells at 8 uM measured after 24 hrs by AnnexinV/7-AAD staining based flow cytometric analysis (Rvb = 1.86%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4338685 | F | Induction of apoptosis in human MDA-MB-468 cells assessed as necrotic cells at 8 uM measured after 24 hrs by AnnexinV/7-AAD staining based flow cytometric analysis (Rvb = 0.62%) | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!