| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4404977 | F | Antibacterial activity against Pseudomonas aeruginosa assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | Pseudomonas aeruginosa | 7 | organism-based format | Scientific Literature | ||
| 2. | ALA4404979 | F | Antifungal activity against Candida albicans assessed as reduction in fungal growth incubated for 24 hrs by broth microdilution method | Candida albicans | 7 | organism-based format | Scientific Literature | ||
| 3. | ALA4404984 | F | Antibacterial activity against methicillin-sensitive Staphylococcus aureus assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | Staphylococcus aureus | 5 | organism-based format | Scientific Literature | ||
| 4. | ALA4404985 | F | Antibacterial activity against methicillin-resistance Staphylococcus aureus assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | Staphylococcus aureus | 5 | organism-based format | Scientific Literature | ||
| 5. | ALA4404986 | F | Antibacterial activity against vancomycin-resistant Enterococcus assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | Enterococcus | 5 | organism-based format | Scientific Literature | ||
| 6. | ALA4404987 | F | Antibacterial activity against multidrug-resistant Acinetobacter baumannii assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | Acinetobacter baumannii | 5 | organism-based format | Scientific Literature | ||
| 7. | ALA4404988 | F | Antibacterial activity against Carbapenem-Resistant Enterobacteriaceae assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | Enterobacteriaceae | 5 | organism-based format | Scientific Literature | ||
| 8. | ALA4404989 | A | Cytotoxicity against HDF cells assessed as cell viability at 500 ug/ml incubated for 24 hrs by MTS assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4404990 | A | Cytotoxicity against HDF cells assessed as truncation and reduction in cytoskeleton at 500 ug/ml incubated for 24 hrs by Alexa Fluor 569 phalloidin-FITC/Hoescht dye staining based fluorescence microscopic analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4404991 | A | Cytotoxicity against human HaCaT cells assessed as truncation and reduction in cytoskeleton at 500 ug/ml incubated for 24 hrs by Alexa Fluor 569 phalloidin-FITC/Hoescht dye staining based fluorescence microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4404992 | A | Hemolytic activity against human erythrocytes assessed as hemoglobin release incubated for 1 hr | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4404993 | F | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 29212 assessed as log10 reduction in bacterial viability at 2 to 4 times MIC incubated for 30 mins in MHB medium followed by reincubation on MH agar plate for 24 to 48 hrs by time kill kinetics analysis | Enterococcus faecalis | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA4404994 | F | Antibacterial activity against vancomycin-resistant Enterococcus faecalis 1010 assessed as log10 reduction in bacterial viability at 2 to 4 times MIC incubated for 30 mins in MHB medium followed by reincubation on MH agar plate for 24 to 48 hrs by time kill kinetics analysis | Enterococcus faecalis | 3 | organism-based format | Scientific Literature | ||
| 14. | ALA4404995 | F | Antibacterial activity against vancomycin-resistant Enterococcus faecalis 1002 assessed as log10 reduction in bacterial viability at 2 to 4 times MIC incubated for 30 mins in MHB medium followed by reincubation on MH agar plate for 24 to 48 hrs by time kill kinetics analysis | Enterococcus faecalis | 3 | organism-based format | Scientific Literature | ||
| 15. | ALA4404996 | F | Antibacterial activity against Acinetobacter baumannii 1001 assessed as reduction in bacterial viability at 2 or 4 times MIC incubated up to 24 hrs in MHB medium followed by reincubation on MH agar plate for 24 to 48 hrs by time kill kinetics assay | Acinetobacter baumannii | 3 | organism-based format | Scientific Literature | ||
| 16. | ALA4404997 | F | Antibacterial activity against Escherichia coli 1004 assessed as reduction in bacterial viability at 2 or 4 times MIC incubated up to 24 hrs in MHB medium followed by reincubation on MH agar plate for 24 to 48 hrs by time kill kinetics assay | Escherichia coli | 3 | organism-based format | Scientific Literature | ||
| 17. | ALA4404998 | F | Antibacterial activity against Klebsiella pneumoniae 1008 assessed as reduction in bacterial viability at 2 or 4 times MIC incubated up to 24 hrs in MHB medium followed by reincubation on MH agar plate for 24 to 48 hrs by time kill kinetics assay | Klebsiella pneumoniae | 3 | organism-based format | Scientific Literature | ||
| 18. | ALA4404999 | B | Induction of pore formation in intact vancomycin-resistant Enterococcus faecalis ATCC 29212 cell membrane assessed as SG uptake at 2 times MIC by SG dye based fluorescence based assay | Enterococcus faecalis | 3 | organism-based format | Scientific Literature | ||
| 19. | ALA4405000 | B | Induction of pore formation in intact vancomycin-resistant Enterococcus faecalis 1002 cell membrane assessed as SG uptake at 2 times MIC by SG dye based fluorescence based assay | Enterococcus faecalis | 3 | organism-based format | Scientific Literature | ||
| 20. | ALA4405001 | B | Induction of pore formation in intact Acinetobacter baumannii 1001 cell membrane assessed as SG uptake at 2 times MIC by SG dye based fluorescence based assay | Acinetobacter baumannii | 3 | organism-based format | Scientific Literature |
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