#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4377390	A	Inhibition of JAK1/JAK3 in human PBMC assessed as decrease in IL2-induced STAT5 phosphorylation in CD3+ T cells preincubated for 1 hr followed by stimulation with IL2 for 15 mins by flow cytometry	Homo sapiens	2	ALA4376812	cell-based format	Scientific Literature
2.	ALA4377397	B	Selectivity ratio of IC50 for JAK1/JAK3 in human PBMC assessed as decrease in IL2-induced STAT5 phosphorylation in CD3+ T cells to IC50 for TYK2 JH2 domain in human PBMC assessed as decrease in IFNalpha-induced STAT5 phosphorylation	Homo sapiens	2	ALA4376812	cell-based format	Scientific Literature
3.	ALA4377470	A	Inhibition of fluorescein labeled probe binding to human recombinant JAK3 JH1 domain incubated for 1 hr by HTRF assay	Homo sapiens	2	ALA4376812	single protein format	Scientific Literature
4.	ALA4377476	A	Inhibition of JAK2 in GM-CSF-stimulated human TF-1 cells	Homo sapiens	1	ALA4376812	cell-based format	Scientific Literature
5.	ALA4377477	B	Selectivity ratio of IC50 for JAK2 in GM-CSF-stimulated human TF-1 cells to IC50 for TYK2 JH2 domain in human PBMC assessed as decrease in IFNalpha-induced STAT5 phosphorylation	Homo sapiens	1	ALA4376812	assay format	Scientific Literature
6.	ALA4377482	B	Selectivity ratio of IC50 for c-kit (unknown origin) to IC50 for His-tagged recombinant human TYK2 pseudokinase JH2 domain (575-869 residues) incubated for 1 hr by HTRF assay	Homo sapiens	1	ALA4376812	assay format	Scientific Literature
7.	ALA4414785	B	Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mins by HTRF assay	Homo sapiens	22	ALA4414548	single protein format	Scientific Literature
8.	ALA4414786	B	Inhibition of TYK2 JH1 domain (unknown origin)	Homo sapiens	10	ALA4414548	single protein format	Scientific Literature
9.	ALA4414787	B	Inhibition of JAK1 JH1 domain (unknown origin)	Homo sapiens	10	ALA4414548	single protein format	Scientific Literature
10.	ALA4414788	B	Inhibition of JAK2 JH1 domain (unknown origin)	Homo sapiens	10	ALA4414548	single protein format	Scientific Literature
11.	ALA4414790	B	Inhibition of TYK2/JAK1 in IFNalpha-stimulated human Kit225 cells by steady-glo luciferase assay	Homo sapiens	27	ALA4414548	assay format	Scientific Literature
12.	ALA4414793	B	Inhibition of TYK2 JH2 domain in human whole blood assessed as inhibition of IFNalpha-induced STAT5 phosphorylation preincubated for 1 hr followed by IFNalpha stimulation and measured after 15 mins by fluorescence assay	Homo sapiens	20	ALA4414548	tissue-based format	Scientific Literature
13.	ALA4414795	A	Permeability across apical to basolateral side in human Caco2 cells	Homo sapiens	17	ALA4414548	cell-based format	Scientific Literature
14.	ALA4414796	A	Efflux ratio of permeability in human Caco2	Homo sapiens	17	ALA4414548	cell-based format	Scientific Literature
15.	ALA4414800	B	Inhibition of TYK2 JH2 domain in mouse whole blood assessed as inhibition of IFNalpha-induced STAT1 phosphorylation preincubated for 1 hr followed by IFNalpha stimulation and measured after 15 mins by fluorescence assay	Mus musculus	8	ALA4414548	tissue-based format	Scientific Literature
16.	ALA4414832	A	Half life in human liver microsomes	Homo sapiens	6	ALA4414548	microsome format	Scientific Literature
17.	ALA4414833	A	Half life in rat liver microsomes	Rattus norvegicus	6	ALA4414548	microsome format	Scientific Literature
18.	ALA4414834	A	Half life in mouse liver microsomes	Mus musculus	6	ALA4414548	microsome format	Scientific Literature
19.	ALA4414835	A	Half life in cynomolgus monkey liver microsomes	Macaca fascicularis	6	ALA4414548	microsome format	Scientific Literature
20.	ALA4414836	A	Half life in dog liver microsomes	Canis lupus familiaris	6	ALA4414548	microsome format	Scientific Literature