| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4428688 | B | Inhibition of human adenosine kinase assessed as reduction in conversion of adenosine to AMP | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 2. | ALA4479551 | B | Inhibition of DOT1L (unknown origin) using chicken nucleosome as substrate in presence of [3H]SAM incubated for 1 hr by TopCount method | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 3. | ALA4812131 | F | Antitrypanosomal activity against nifurtimox-sensitive Trypanosoma cruzi Tulahuen CL2 infected in human MRC-5 SV2 cells assessed as inhibition of parasite growth measured after 7 days by spectrophotometric analysis | Trypanosoma cruzi | 80 | organism-based format | Scientific Literature | ||
| 4. | ALA4812132 | A | Cytotoxicity against human MRC-5 SV2 cells assessed as reduction in cell growth measured after 3 days by resazurin dye based fluorometric analysis | Homo sapiens | 79 | cell-based format | Scientific Literature | ||
| 5. | ALA4812133 | T | Selectivity index, ratio of CC50 for human MRC-5 SV2 cells to IC50 for antitrypanosomal activity against nifurtimox-sensitive Trypanosoma cruzi Tulahuen CL2 infected in human MRC-5 SV2 cells | 55 | cell-based format | Scientific Literature | |||
| 6. | ALA4812134 | F | Antileishmanial activity against amastigote form of Leishmania infantum MHOM/MA(BE)/67 infected in Swiss mouse peritoneal macrophages assessed as reduction in parasite growth treated at 2 hrs post-infection and measured after 5 days by Giemsa staining based microscopic analysis | Leishmania infantum | 80 | organism-based format | Scientific Literature | ||
| 7. | ALA4812135 | A | Cytotoxicity against Swiss mouse peritoneal macrophages assessed as cell detachment, lysis and granulation measured after 5 days by microscopic analysis | Mus musculus | 79 | cell-based format | Scientific Literature | ||
| 8. | ALA4812136 | T | Selectivity index, ratio of CC50 for Swiss mouse peritoneal macrophages to IC50 for antileishmanial activity against amastigote form of Leishmania infantum MHOM/MA(BE)/67 infected in Swiss mouse peritoneal macrophages | 30 | assay format | Scientific Literature |
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