# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4356410 | F | Cytotoxicity in human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by FMCA analysis | Homo sapiens | 2 | ALA4354818 | cell-based format | Scientific Literature | |
2. | ALA4356411 | B | Inhibition of 26S proteasome (unknown origin) incubated for 2 hrs by proteasome Ub-Rho cleavage assay | Homo sapiens | 2 | ALA4354818 | assay format | Scientific Literature | |
3. | ALA4358855 | F | Cytotoxicity in human U2OS cells assessed as reduction in cell viability incubated for 72 hrs Cell-titer Glo reagent based assay | Homo sapiens | 2 | ALA4354861 | cell-based format | Scientific Literature | |
4. | ALA4358884 | B | Inhibition of recombinant purified CIAPIN1 (unknown origin) assessed as accumulation of protein aggregates at 0.1 to 1.6 uM incubated for 1 to 6 hrs by size exclusion chromatography | Homo sapiens | 1 | ALA4354861 | single protein format | Scientific Literature | |
5. | ALA4358893 | B | Inhibition of deubiquitinase in human HeLa cell extracts assessed as inhibition of HA-Ub-C2Br probe labeling at 1 to 100 uM incubated for 30 mins by immunoblot analysis | Homo sapiens | 2 | ALA4354861 | cell-based format | Scientific Literature | |
6. | ALA4358894 | B | Inhibition of USP28 in human HeLa cell extracts assessed as inhibition of HA-Ub-C2Br probe labeling at 1 to 100 uM incubated for 30 mins by immunoblot analysis | Homo sapiens | 2 | ALA4354861 | cell-based format | Scientific Literature | |
7. | ALA4358895 | F | Cytotoxicity in human KMS11 cells assessed as reduction in cell viability at 1 to 10 uM incubated for 16 hrs in presence of GSH by Alamar blue assay | Homo sapiens | 2 | ALA4354861 | cell-based format | Scientific Literature | |
8. | ALA4358896 | F | Cytotoxicity in human KMS11 cells assessed as reduction in cell viability incubated for 72 hrs Cell-titer Glo reagent based assay | Homo sapiens | 2 | ALA4354861 | cell-based format | Scientific Literature | |
9. | ALA4358897 | B | Covalent binding affinity to UCH-37 in human U2OS cells at 20 uM using probe-1 by ABPP analysis | Homo sapiens | 1 | ALA4354861 | cell-based format | Scientific Literature | |
10. | ALA4358898 | B | Covalent binding affinity to USP14 in human U2OS cells at 20 uM using probe-1 by ABPP analysis | Homo sapiens | 1 | ALA4354861 | cell-based format | Scientific Literature | |
11. | ALA4358899 | B | Covalent binding affinity to USP28 in human U2OS cells at 20 uM using probe-1 by ABPP analysis | Homo sapiens | 1 | ALA4354861 | cell-based format | Scientific Literature | |
12. | ALA4358900 | B | Covalent binding affinity to CIAPIN1 in human U2OS cells at 20 uM using probe-1 by ABPP analysis | Homo sapiens | 1 | ALA4354861 | cell-based format | Scientific Literature | |
13. | ALA4358901 | B | Inhibition of CIAPIN1 in human KMS11 crude cell extracts assessed as induction of formation of high molecular weight complexes with CIAPIN1 at 20 uM incubated for 2 hrs by immunoblot analysis | Homo sapiens | 1 | ALA4354861 | single protein format | Scientific Literature | |
14. | ALA4358902 | B | Inhibition of CIAPIN1 in human KMS11 crude cell extracts assessed as induction of formation of high molecular weight complexes with CIAPIN1 at 20 uM incubated for 2 hrs in presence of GSH by immunoblot analysis | Homo sapiens | 1 | ALA4354861 | single protein format | Scientific Literature | |
15. | ALA4358903 | B | Inhibition of recombinant purified CIAPIN1 (unknown origin) assessed as increase in high molecular weight CIAPIN1 complexes at 1 to 10 molar equivalent 1 by SDS-PAGE and Coomassie Blue staining based method | Homo sapiens | 1 | ALA4354861 | single protein format | Scientific Literature | |
16. | ALA4358904 | B | Inhibition of recombinant purified CIAPIN1 (unknown origin) assessed as covalent adduct formation at 10 molar equivalents incubated for 2 hrs by electrospray MS analysis | Homo sapiens | 1 | ALA4354861 | single protein format | Scientific Literature | |
17. | ALA4358905 | B | Inhibition of recombinant purified CIAPIN1 (unknown origin) assessed as covalent modification of cysteine residues incubated for 2 hrs LC-MS/MS analysis | Homo sapiens | 1 | ALA4354861 | single protein format | Scientific Literature | |
18. | ALA4358906 | B | Inhibition of recombinant purified CIAPIN1 (unknown origin) assessed as disruption of intra-chain disulfide bond in unmodified peptide containing Cys249 | Homo sapiens | 1 | ALA4354861 | single protein format | Scientific Literature | |
19. | ALA4358907 | B | Inhibition of CIAPIN1 in human KMS11 cells assessed as induction of protein aggregation at 100 nM incubated for 1 hr by immunoblot analysis | Homo sapiens | 1 | ALA4354861 | cell-based format | Scientific Literature | |
20. | ALA4358908 | B | Inhibition of CIAPIN1 in human KMS11 cells assessed as induction of high molecular weight complex formation at 100 nM incubated for 6 hrs by immunoblot analysis | Homo sapiens | 1 | ALA4354861 | cell-based format | Scientific Literature |