| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4394243 | B | Inhibition of human ERG by patch clamp method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 2. | ALA4394244 | A | Inhibition of CYP2D6 (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA4394245 | A | Inhibition of CYP3A4 (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA4394246 | A | Inhibition of CYP1A2 (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4394247 | A | Inhibition of CYP2C9 (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4394248 | A | Apparent permeability from apical to basolateral side in human Caco2 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4394249 | A | Efflux ratio of apparent permeability in human Caco2 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4394250 | A | Intrinsic clearance in human liver microsomes at 1 uM | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 9. | ALA4394251 | A | Inhibition of CYP2C19 (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4394252 | B | Antagonist activity at Smo receptor in mouse NIH/3T3 cells harboring GRE-Luc assessed as inhibition of SAG-induced Hh signaling pathway preincubated with cells followed by SAG addition measured after 48 hrs by luciferase reporter gene assay | Mus musculus | 28 | cell-based format | Scientific Literature | ||
| 11. | ALA4394254 | F | Antiproliferative activity against mouse Ptch+/- medulloblastoma cells assessed as inhibition of cell growth incubated for 36 hrs by CCK-8 assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4394255 | A | Cytotoxicity activity human U251 cells assessed as reduction of cell viability upto 1000 nM incubated for 48 hrs by CCK-8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4394256 | B | Antagonist activity at Smo receptor in mouse NIH/3T3 cells assessed as inhibition of Gli1 mRNA expression incubated for 48 hrs by qRT-PCR analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4394257 | B | Antagonist activity at Smo D473H mutant receptor in mouse NIH/3T3 cells assessed as inhibition of Gli1 mRNA expression incubated for 48 hrs by qRT-PCR analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4394258 | A | Intrinsic clearance in rat liver microsomes at 1 uM | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 16. | ALA4394259 | A | Half life in human liver microsomes at 1 uM | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 17. | ALA4394260 | A | Half life in rat liver microsomes at 1 uM | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 18. | ALA4394262 | B | Inhibition of hedgehog pathway in HEK293 cells harbouring TCF-luciferase cocultured with LWnt3A cells by Topflash reporter gene assay | Homo sapiens | 20 | cell-based format | Scientific Literature |
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