# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4424064 | B | Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes measured after 48 hrs | Human immunodeficiency virus 1 | 21 | ALA4422649 | cell-based format | Scientific Literature | |
2. | ALA4424065 | A | Cytotoxicity against human TZM-b1 cells assessed as reduction in cell viability by CCK8 assay | Homo sapiens | 21 | ALA4422649 | cell-based format | Scientific Literature | |
3. | ALA4424066 | P | Aqueous solubility of the compound in phosphate buffered saline | 3 | ALA4422649 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4424067 | B | Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes by measuring combination index at 450:1 ratio of test compound to KD-247 measured after 48 hrs | Human immunodeficiency virus 1 | 3 | ALA4422649 | cell-based format | Scientific Literature | |
5. | ALA5133924 | B | CD4 mimetic activity at gp120 in HIV-1 KP-5mvcR infected in human TZM-bl cells assessed as inhibition of viral entry by measuring reduction in RLU by single round assay | Human immunodeficiency virus 1 | 11 | ALA5131454 | cell-based format | Scientific Literature | |
6. | ALA5133925 | T | Cytotoxicity against human TZM-bl cells assessed as reduction in cell viability by CellTiter-Glo 2.0 assay | Homo sapiens | 11 | ALA5131454 | cell-based format | Scientific Literature | |
7. | ALA5133926 | P | Aqueous solubility of the compound in PBS at pH 7.4 at 25 degC | 9 | ALA5131454 | small-molecule physicochemical format | Scientific Literature |