# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4361683 | B | Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane | Rattus norvegicus | 17 | cell membrane format | Scientific Literature | ||
2. | ALA4361684 | B | Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane | Rattus norvegicus | 17 | cell membrane format | Scientific Literature | ||
3. | ALA4361685 | B | Selectivity index, ratio of Ki for alpha7 nAChR in rat hippocampus membrane to Ki for alpha4beta2 nAChR in rat cerebral cortex membrane | Rattus norvegicus | 16 | cell membrane format | Scientific Literature | ||
4. | ALA4361686 | B | Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
5. | ALA4361687 | B | Selectivity index, ratio of Ki for human alpha3beta4 nAChR in HEK243 cell membrane to Ki for alpha4beta2 nAChR in rat cerebral cortex membrane | 16 | cell-based format | Scientific Literature | |||
6. | ALA4361688 | B | Agonist activity at human alpha4beta2 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70 mV holding potential by patch clamp assay relative to acetylcholine | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA4361689 | B | Agonist activity at human alpha4beta2 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70 mV holding potential by patch clamp assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
8. | ALA4361692 | B | Agonist activity at human alpha3beta4 nAChR expressed in GH4C1 cells assessed as inward channel current at 0.01 to 100 uM measured after 3 to 4 days at -70 mV holding potential by patch clamp assay | Homo sapiens | 1 | cell-based format | Scientific Literature |