# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4388737 | A | Time dependent inhibition of CYP3A4 in human liver microsomes assessed as enzyme residual activity at 100 uM relative to control | Homo sapiens | 7 | microsome format | Scientific Literature | ||
2. | ALA4388738 | A | Inhibition of CYP1A2 (unknown origin) at 10 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
3. | ALA4388739 | B | Induction of alkaline phosphatase activity in mouse ST-2 cells after 4 days by spectrophotometric method | Mus musculus | 37 | cell-based format | Scientific Literature | ||
4. | ALA4388740 | P | Solubility of the compound in pH 6.8 JP2 solution | 7 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA4388741 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining after 30 mins | Homo sapiens | 7 | microsome format | Scientific Literature | ||
6. | ALA4388742 | A | Metabolic stability in rat liver microsomes assessed as parent compound remaining after 30 mins | Rattus norvegicus | 7 | microsome format | Scientific Literature | ||
7. | ALA4388743 | A | Inhibition of CYP2C9 (unknown origin) at 10 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
8. | ALA4388744 | A | Inhibition of CYP2C19 (unknown origin) at 10 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
9. | ALA4388745 | A | Inhibition of CYP2D6 (unknown origin) at 10 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
10. | ALA4388746 | A | Inhibition of CYP3A4 (unknown origin) at 10 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
11. | ALA4388749 | A | Cmax in F344 rat at 60 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
12. | ALA4388750 | A | AUC (0 to 8 hrs) in F344 rat at 60 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature |