# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4377237 | F | Cytotoxicity against human LO2 cells after 72 hrs by MTT assay | Homo sapiens | 1 | ALA4376807 | cell-based format | Scientific Literature | |
2. | ALA4377238 | F | Antiproliferative activity against human Bel7402/5-FU cells at 0.2 to 5 uM after 72 hrs by MTT assay | Homo sapiens | 1 | ALA4376807 | cell-based format | Scientific Literature | |
3. | ALA4377239 | F | Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4376807 | cell-based format | Scientific Literature | |
4. | ALA4377240 | F | Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4376807 | cell-based format | Scientific Literature | |
5. | ALA4377241 | F | Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4376807 | cell-based format | Scientific Literature | |
6. | ALA4377242 | F | Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4376807 | cell-based format | Scientific Literature | |
7. | ALA4377243 | B | Inhibition of HDAC1 (unknown origin) using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins by fluorimetric assay | Homo sapiens | 8 | ALA4376807 | single protein format | Scientific Literature | |
8. | ALA4377244 | B | Inhibition of human HDAC3 using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins by fluorimetric assay | Homo sapiens | 3 | ALA4376807 | single protein format | Scientific Literature | |
9. | ALA4377245 | B | Inhibition of human HDAC6 using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins by fluorimetric assay | Homo sapiens | 3 | ALA4376807 | single protein format | Scientific Literature | |
10. | ALA4377246 | B | Inhibition of human HDAC8 using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins by fluorimetric assay | Homo sapiens | 3 | ALA4376807 | single protein format | Scientific Literature | |
11. | ALA4377247 | F | Antiproliferative activity against human Bel7402 cells at 0.2 to 5 uM after 72 hrs by MTT assay | Homo sapiens | 1 | ALA4376807 | cell-based format | Scientific Literature | |
12. | ALA4377248 | B | Selectivity ratio of IC50 for HDAC1 (unknown origin) to IC50 for human HDAC6 | Homo sapiens | 2 | ALA4376807 | assay format | Scientific Literature | |
13. | ALA4377249 | B | Selectivity ratio of IC50 for human HDAC3 to IC50 for human HDAC6 | Homo sapiens | 2 | ALA4376807 | assay format | Scientific Literature | |
14. | ALA4377250 | B | Inhibition of HDAC in human Bel7402 cells assessed as increase in acetylated histone h3 expression incubated for 72 hrs by Western blot analysis | Homo sapiens | 1 | ALA4376807 | cell-based format | Scientific Literature | |
15. | ALA4377251 | B | Inhibition of HDAC in human Bel7402 cells assessed as increase in acetylated alpha-tubulin expression incubated for 72 hrs by Western blot analysis | Homo sapiens | 1 | ALA4376807 | cell-based format | Scientific Literature | |
16. | ALA4377254 | F | Induction of apoptosis in human Bel7402 cells assessed as annexin-V positive cells at 1 uM after 72 hrs by Annexin-V/PI staining based flow cytometry relative to control | Homo sapiens | 1 | ALA4376807 | cell-based format | Scientific Literature | |
17. | ALA4377255 | F | Induction of apoptosis in human Bel7402 cells assessed as annexin-V positive cells at 5 uM after 72 hrs by Annexin-V/PI staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4376807 | cell-based format | Scientific Literature | |
18. | ALA4377257 | F | Induction of apoptosis in human Bel7402 cells assessed as increase in Bax expression after 72 hrs by Western blot analysis | Homo sapiens | 1 | ALA4376807 | cell-based format | Scientific Literature | |
19. | ALA4377258 | F | Induction of apoptosis in human Bel7402 cells assessed as decrease in Bcl-2 expression after 72 hrs by Western blot analysis | Homo sapiens | 1 | ALA4376807 | cell-based format | Scientific Literature | |
20. | ALA4377259 | F | Induction of apoptosis in human Bel7402 cells assessed as increase in cleaved caspase-3 level at 1 uM after 72 hrs by Western blot analysis | Homo sapiens | 1 | ALA4376807 | cell-based format | Scientific Literature |