# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4368044 | F | Antiproliferative activity against human CEM cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay | Homo sapiens | 9 | ALA4364315 | cell-based format | Scientific Literature | |
2. | ALA4368045 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay | Homo sapiens | 9 | ALA4364315 | cell-based format | Scientific Literature | |
3. | ALA4368046 | F | Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay | Homo sapiens | 9 | ALA4364315 | cell-based format | Scientific Literature | |
4. | ALA4368047 | F | Antiproliferative activity against human A2780 cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay | Homo sapiens | 9 | ALA4364315 | cell-based format | Scientific Literature | |
5. | ALA4368048 | F | Antiproliferative activity against human Hep3B cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay | Homo sapiens | 9 | ALA4364315 | cell-based format | Scientific Literature | |
6. | ALA4368049 | A | Cytotoxicity against human BJ cells assessed as reduction in cell viability after 72 hrs by resazurin dye based assay | Homo sapiens | 9 | ALA4364315 | cell-based format | Scientific Literature | |
7. | ALA4368050 | B | Inhibition of porcine kidney Na+/K+-ATPase assessed as residual activity at 50 uM preincubated for 2 mins followed by ATP addition and measured after 6 mins by bagin-sky assay relative to untreated control | Sus scrofa | 9 | ALA4364315 | protein complex format | Scientific Literature | |
8. | ALA4368056 | F | Cell cycle arrest in human CEM cells assessed as accumulation of cells at sub-G1 phase at 15 uM after 24 hrs by RNase A/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 4 | ALA4364315 | cell-based format | Scientific Literature | |
9. | ALA4368058 | F | Induction of apoptosis in human CEM cells assessed as increase in relative activity of caspase-3/7 at 15 uM using AC-DEVD-AMC as substrate after 24 hrs by fluorescence based assay | Homo sapiens | 3 | ALA4364315 | cell-based format | Scientific Literature | |
10. | ALA4368060 | F | Induction of apoptosis in human CEM cells assessed as PARP-1 cleavage at 15 uM after 24 hrs by Western blot analysis | Homo sapiens | 4 | ALA4364315 | cell-based format | Scientific Literature | |
11. | ALA4368061 | F | Induction of apoptosis in human CEM cells assessed as caspase-7 fragmentation at 15 uM after 24 hrs by Western blot analysis | Homo sapiens | 4 | ALA4364315 | cell-based format | Scientific Literature | |
12. | ALA4368062 | F | Induction of apoptosis in human CEM cells assessed as decrease in Mcl-1 expression at 15 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4364315 | cell-based format | Scientific Literature |