# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4378611 | ADME | Drug level in beta-naphthoflavone/phenobarbital-induced rat liver S9 fraction treated with 100 ug/ml Ezutromid-1 assessed as compound formation in presence of NADPH measured after 4 hrs by UV-Vis spectroscopy | Rattus norvegicus | 2 | ALA4376826 | subcellular format | Scientific Literature | |
2. | ALA4378613 | ADME | Retention time in beta-naphthoflavone/phenobarbital-induced rat liver S9 fraction at 100 ug/ml in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 2 | ALA4376826 | subcellular format | Scientific Literature | |
3. | ALA4378614 | ADME | Retention time in human plasma by LC-MS/MS analysis | Homo sapiens | 2 | ALA4376826 | cell-free format | Scientific Literature | |
4. | ALA4378667 | ADME | Activation of human utrophin-1 in mouse mdx myoblasts by H2K-mdx utrnA-luc assay | Homo sapiens | 3 | ALA4376826 | single protein format | Scientific Literature | |
5. | ALA4378668 | ADME | Activation of human utrophin-1 in iDMD cells by HTRF assay | Homo sapiens | 3 | ALA4376826 | cell-based format | Scientific Literature | |
6. | ALA4378669 | Physicochemical | Lipophilicity, logD of the compound at pH 7.4 | 3 | ALA4376826 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4378670 | Physicochemical | Kinetic aqueous solubility of the compound | 3 | ALA4376826 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA4378671 | ADME | Permeability at pH 7.4 by PAMPA | 3 | ALA4376826 | assay format | Scientific Literature | ||
9. | ALA4378672 | ADME | Protein binding in mouse plasma assessed as bound fraction | Mus musculus | 3 | ALA4376826 | cell-free format | Scientific Literature | |
10. | ALA4378673 | ADME | Protein binding in human plasma assessed as bound fraction | Homo sapiens | 3 | ALA4376826 | cell-free format | Scientific Literature | |
11. | ALA4378674 | ADME | Half life in mouse liver S9 fraction | Mus musculus | 3 | ALA4376826 | subcellular format | Scientific Literature | |
12. | ALA4378675 | ADME | Half life in mouse hepatocytes | Mus musculus | 2 | ALA4376826 | cell-based format | Scientific Literature | |
13. | ALA4378676 | ADME | Drug metabolism assessed as human UGT1A4-mediated metabolism by measuring intrinsic clearance | Homo sapiens | 2 | ALA4376826 | single protein format | Scientific Literature | |
14. | ALA4378677 | ADME | Half life in human liver S9 fraction | Homo sapiens | 3 | ALA4376826 | subcellular format | Scientific Literature | |
15. | ALA4378678 | ADME | Half life in human hepatocytes | Homo sapiens | 2 | ALA4376826 | cell-based format | Scientific Literature | |
16. | ALA4378679 | ADME | Intrinsic clearance in mouse liver S9 fraction | Mus musculus | 3 | ALA4376826 | subcellular format | Scientific Literature | |
17. | ALA4378680 | ADME | Intrinsic clearance in mouse hepatocytes | Mus musculus | 2 | ALA4376826 | cell-based format | Scientific Literature | |
18. | ALA4378681 | ADME | Intrinsic clearance in human liver S9 fraction | Homo sapiens | 3 | ALA4376826 | subcellular format | Scientific Literature | |
19. | ALA4378682 | ADME | Intrinsic clearance in human hepatocytes | Homo sapiens | 2 | ALA4376826 | cell-based format | Scientific Literature | |
20. | ALA4378685 | ADME | Drug metabolism assessed as human UGT-mediated metabolism by measuring intrinsic clearance | Homo sapiens | 2 | ALA4376826 | protein format | Scientific Literature |