# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4337378 | B | Displacement of 3 nM [3H]Nalpha-methylhistamine from human H3R expressed in Sf9 cell membranes co-expressing Gia2 and beta1gamma2 by competition binding assay | Homo sapiens | 17 | ALA4334488 | cell-based format | Scientific Literature | |
2. | ALA4337390 | B | Displacement of 40 nM [3H]-histamine from human H4R expressed in Sf9 cell membranes co-expressing Gia2 and beta1gamma2 by competition binding assay | Homo sapiens | 9 | ALA4334488 | cell-based format | Scientific Literature | |
3. | ALA4337391 | B | Displacement of 2 nM [3H]UR-PI294 from human H3R expressed in Sf9 cell membranes co-expressing Gia2 and beta1gamma2 by competition binding assay | Homo sapiens | 8 | ALA4334488 | cell-based format | Scientific Literature | |
4. | ALA4337392 | B | Displacement of 20 nM [3H]UR-DE257 from human H2R expressed in Sf9 cell membranes co-expressing GsalphaS by competition binding assay | Homo sapiens | 20 | ALA4334488 | cell-based format | Scientific Literature | |
5. | ALA4337393 | B | Displacement of 5 nM [3H-pyrilamine from human H1R expressed in Sf9 cell membranes co-expressing RGS4 by competition binding assay | Homo sapiens | 20 | ALA4334488 | cell-based format | Scientific Literature | |
6. | ALA4337395 | B | Selectivity index, ratio of Ki for displacement of 2 nM [3H]UR-PI294 from human H3R expressed in Sf9 cell membranes co-expressing Gia2 and beta1gamma2 by competition binding assay to Ki for displacement of 40 nM [3H]-histamine from human H4R expressed in Sf9 cell membranes co-expressing Gia2 and beta1gamma2 by competition binding assay | Homo sapiens | 9 | ALA4334488 | cell-based format | Scientific Literature | |
7. | ALA4337397 | B | Selectivity index, ratio of Ki for [3H]UR-DE257 from human H2R expressed in Sf9 cell membranes co-expressing GsalphaS by competition binding assay to Ki for displacement of 40 nM [3H]-histamine from human H4R expressed in Sf9 cell membranes co-expressing Gia2 and beta1gamma2 by competition binding assay | Homo sapiens | 7 | ALA4334488 | cell-based format | Scientific Literature | |
8. | ALA4337398 | F | Agonist activity at human H4R expressed in HEK293-SF-hH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assay | Homo sapiens | 9 | ALA4334488 | cell-based format | Scientific Literature | |
9. | ALA4337399 | F | Intrinsic agonist activity at human H4R expressed in HEK293-SF-hH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assay relative to histamine | Homo sapiens | 8 | ALA4334488 | cell-based format | Scientific Literature | |
10. | ALA4337400 | B | Agonist activity at human H4R expressed in HEK293T-beta-arr2-hH4R cells by beta-arrestin2 recruitment assay | Homo sapiens | 9 | ALA4334488 | cell-based format | Scientific Literature | |
11. | ALA4337401 | B | Intrinsic agonist activity at human H4R expressed in HEK293T-beta-arr2-hH4R cells by beta-arrestin2 recruitment assay relative to histamine | Homo sapiens | 8 | ALA4334488 | cell-based format | Scientific Literature | |
12. | ALA4337402 | F | Agonist activity at mouse H4R expressed in HEK293-SF-mH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assay | Mus musculus | 9 | ALA4334488 | cell-based format | Scientific Literature | |
13. | ALA4337403 | F | Intrinsic agonist activity at mouse H4R expressed in HEK293-SF-mH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assay relative to histamine | Mus musculus | 8 | ALA4334488 | cell-based format | Scientific Literature | |
14. | ALA4337404 | B | Agonist activity at mouse H4R expressed in HEK293T-beta-arr2-mH4R cells by beta-arrestin2 recruitment assay | Mus musculus | 9 | ALA4334488 | cell-based format | Scientific Literature | |
15. | ALA4337405 | B | Intrinsic agonist activity at mouse H4R expressed in HEK293T-beta-arr2-mH4R cells by beta-arrestin2 recruitment assay relative to histamine | Mus musculus | 8 | ALA4334488 | cell-based format | Scientific Literature | |
16. | ALA4337406 | F | Agonist activity at rat H4R expressed in HEK293-SF-rH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assay | Rattus norvegicus | 9 | ALA4334488 | cell-based format | Scientific Literature | |
17. | ALA4337407 | F | Intrinsic agonist activity at rat H4R expressed in HEK293-SF-rH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assay relative to histamine | Rattus norvegicus | 8 | ALA4334488 | cell-based format | Scientific Literature | |
18. | ALA4337408 | B | Agonist activity at rat H4R expressed in HEK293T-beta-arr2-rH4R cells by beta-arrestin2 recruitment assay | Rattus norvegicus | 9 | ALA4334488 | cell-based format | Scientific Literature | |
19. | ALA4337409 | B | Intrinsic agonist activity at rat H4R expressed in HEK293T-beta-arr2-rH4R cells by beta-arrestin2 recruitment assay relative to histamine | Rattus norvegicus | 8 | ALA4334488 | cell-based format | Scientific Literature |