# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA616340 | Binding | Binding affinity against native 5-HT1A-receptors from rat hippocampus using radioligand ([3H]8-hydroxy-2-(di-n-propylamino)-tetraline) binding assay | 5 | ALA1129400 | tissue-based format | Scientific Literature | ||
2. | ALA646244 | Binding | Compound was tested for binding affinity against native Alpha-1B adrenergic receptor from rat liver using radioligand ([3H]prazosin) binding assay | 4 | ALA1129400 | assay format | Scientific Literature | ||
3. | ALA640173 | Binding | Compound was tested for binding affinity against human hippocampus Alpha-1D adrenergic receptor using radioligand ([3H]prazosin) binding assay | 2 | ALA1129400 | tissue-based format | Scientific Literature | ||
4. | ALA642293 | Binding | Binding affinity against native Alpha-2 adrenergic receptor from rat cerebral cortex using radioligand ([3H]rauwolscine) binding assay | 6 | ALA1129400 | tissue-based format | Scientific Literature | ||
5. | ALA648009 | Binding | Compound was tested for binding affinity against cloned Alpha-1D adrenergic receptor from rat brain using radioligand ([3H]prazosin) binding assay | 1 | ALA1129400 | assay format | Scientific Literature | ||
6. | ALA642090 | Binding | Binding affinity against native Alpha-1 adrenergic receptor from rat cerebral cortex using radioligand [3H]-prazosin binding assay | 6 | ALA1129400 | tissue-based format | Scientific Literature | ||
7. | ALA652802 | Binding | Compound was tested for binding affinity against cloned Alpha-1A adrenergic receptor from bovine brain using radioligand ([3H]prazosin) binding assay | 6 | ALA1129400 | assay format | Scientific Literature | ||
8. | ALA643757 | Binding | Compound was tested for binding affinity against human hippocampus Alpha-1A adrenergic receptor using radioligand ([3H]prazosin) binding assay | 2 | ALA1129400 | tissue-based format | Scientific Literature | ||
9. | ALA857770 | Binding | Binding affinity against native Alpha-1A adrenergic receptor from rat hippocampus pretreated with chloroethylclonidine using radioligand ([3H]prazosin) binding assay | 6 | ALA1129400 | tissue-based format | Scientific Literature | ||
10. | ALA648101 | Binding | Compound was tested for binding affinity against cloned Alpha-1B adrenergic receptor from hamster smooth muscle using radioligand ([3H]prazosin) binding assay | Cricetulus griseus | 6 | ALA1129400 | single protein format | Scientific Literature | |
11. | ALA645572 | Binding | Compound was tested for binding affinity against human hippocampus Alpha-1B adrenergic receptor using radioligand ([3H]-prazosin) binding assay | 1 | ALA1129400 | tissue-based format | Scientific Literature | ||
12. | ALA670972 | Binding | Compound was tested for binding affinity against native Dopamine receptor D2 from rat striatum using radioligand [3H]-spiperone) | 5 | ALA1129400 | single protein format | Scientific Literature | ||
13. | ALA4123776 | Functional | Antagonist activity at alpha1A adrenergic receptor in Wistar rat prostatic rat vas deferens assessed as inhibition of noradrenaline-induced contraction preincubated for 30 mins followed by noradrenaline addition measured after 45 mins in presence of cocaine hydrochloride | Rattus norvegicus | 13 | ALA4118202 | assay format | Scientific Literature | |
14. | ALA4123777 | Functional | Antagonist activity at alpha1B adrenergic receptor in Wistar rat spleen assessed as inhibition of phenylephrine-induced contraction incubated for 30 mins in presence of beta-adrenoceptor blocker propranolol hydrochloride | Rattus norvegicus | 13 | ALA4118202 | assay format | Scientific Literature | |
15. | ALA4123778 | Functional | Antagonist activity at alpha1D adrenergic receptor in Wistar rat thoracic aorta assessed as inhibition of noradrenaline-induced contraction measured after 30 mins in presence of cocaine hydrochloride and beta-adrenoceptor blocker propranolol hydrochloride | Rattus norvegicus | 13 | ALA4118202 | assay format | Scientific Literature | |
16. | ALA4123779 | Binding | Selectivity ratio of compound effect for antagonism of alpha1B adrenergic receptor in Wistar rat spleen to compound effect for antagonism of alpha1A adrenergic receptor in Wistar rat prostatic rat vas deferens | Rattus norvegicus | 13 | ALA4118202 | assay format | Scientific Literature | |
17. | ALA4123780 | Binding | Selectivity ratio of compound effect for antagonism of alpha1B adrenergic receptor in Wistar rat spleen to compound effect for antagonism of alpha1D adrenergic receptor in Wistar rat thoracic aorta | Rattus norvegicus | 13 | ALA4118202 | assay format | Scientific Literature | |
18. | ALA4123781 | Binding | Selectivity ratio of compound effect for antagonism of alpha1D adrenergic receptor in Wistar rat thoracic aorta to compound effect for antagonism of alpha1A adrenergic receptor in Wistar rat prostatic rat vas deferens | Rattus norvegicus | 13 | ALA4118202 | assay format | Scientific Literature | |
19. | ALA4123782 | Binding | Displacement of [3H]prazosin from human alpha1A adrenergic receptor expressed in CHO cell membranes after 30 mins by rapid filtration method | Homo sapiens | 12 | ALA4118202 | cell-based format | Scientific Literature | |
20. | ALA4123783 | Binding | Displacement of [3H]prazosin from human alpha1B adrenergic receptor expressed in CHO cell membranes after 30 mins by rapid filtration method | Homo sapiens | 12 | ALA4118202 | cell-based format | Scientific Literature |