# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4315019 | B | Inhibition of human NTPdase-1 expressed in COS7 cell membranes at 100 uM using ATP as substrate preincubated for 3 mins followed by susbtrate addition and measured after 10 mins by malachite green dye based method | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA4315020 | B | Inhibition of human NTPdase-2 expressed in COS7 cell membranes at 100 uM using ATP as substrate preincubated for 3 mins followed by susbtrate addition and measured after 10 mins by malachite green dye based method | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA4315021 | B | Inhibition of human NTPdase-3 expressed in COS7 cell membranes at 100 uM using ATP as substrate preincubated for 3 mins followed by susbtrate addition and measured after 10 mins by malachite green dye based method | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
4. | ALA4315022 | B | Inhibition of human NTPdase-8 expressed in COS7 cell membranes at 100 uM using ATP as substrate preincubated for 3 mins followed by susbtrate addition and measured after 10 mins by malachite green dye based method | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
5. | ALA4315023 | B | Inhibition of human NPP1 expressed in COS7 cell membranes at 100 uM using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition and measured after 15 mins relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
6. | ALA4315024 | B | Inhibition of human NPP3 expressed in COS7 cell membranes at 100 uM using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition and measured after 15 mins relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA4315025 | B | Inhibition of human NPP1 expressed in COS7 cell membranes using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition and measured after 15 mins by Dixon plot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
8. | ALA4315027 | F | Agonist activity at human P2Y2 receptor expressed in AD293 cells assessed as inositol-1-phosphate accumulation at 100 uM | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
9. | ALA4315028 | F | Antagonist activity at human P2Y2 receptor expressed in AD293 cells assessed as inhibition of UTP-induced inositol-1-phosphate accumulation at 100 uM | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
10. | ALA4315030 | F | Agonist activity at human P2Y4 receptor expressed in AD293 cells assessed as inositol-1-phosphate accumulation at 0.1 to 100 uM | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
11. | ALA4315031 | F | Antagonist activity at human P2Y4 receptor expressed in AD293 cells assessed as inhibition of UTP-induced inositol-1-phosphate accumulation at 0.1 to 100 uM | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
12. | ALA4315032 | F | Antagonist activity at human P2Y6 receptor expressed in AD293 cells assessed as inhibition of UDP-induced inositol-1-phosphate accumulation at 0.1 to 100 uM | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
13. | ALA4315033 | F | Agonist activity at human P2Y6 receptor expressed in AD293 cells assessed as inositol-1-phosphate accumulation at 100 uM | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
14. | ALA4315035 | B | Inhibition of alkaline phosphatase in human primary chondrocyte at 100 uM using p-nitrophenyl phosphate as substrate after 30 mins by ELISA relative to control | Homo sapiens | 4 | assay format | Scientific Literature | ||
15. | ALA4315036 | A | Cytotoxicity against human primary chondrocytes at 100 uM after 24 hrs by XTT assay | Homo sapiens | 4 | assay format | Scientific Literature |