| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4410693 | B | Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes at 1 uM incubated for 60 mins by scintillation counting method relative to control | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 2. | ALA4410694 | B | Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes at 1 uM incubated for 120 mins by scintillation counting method relative to control | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 3. | ALA4410695 | B | Inhibition of rat synaptosomes 5HT transporter assessed as reduction in [3H]serotonin reuptake at 1 uM incubated for 15 mins by scintillation counting method relative to control | Rattus norvegicus | 14 | subcellular format | Scientific Literature | ||
| 4. | ALA4410696 | B | Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counting method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4410697 | B | Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4410698 | B | Inhibition of rat synaptosomes 5HT transporter assessed as reduction in [3H]serotonin reuptake incubated for 15 mins by scintillation counting method | Rattus norvegicus | 3 | subcellular format | Scientific Literature | ||
| 7. | ALA4410699 | A | Half life in rat liver microsomes at 1 uM in presence of NADPH generating system measured for 10 to 90 mins by LC-MS/MS analysis | Rattus norvegicus | 4 | microsome format | Scientific Literature | ||
| 8. | ALA4410700 | A | Clearance in rat liver microsomes at 1 uM in presence of NADPH generating system measured for 10 to 90 mins by LC-MS/MS analysis | Rattus norvegicus | 4 | microsome format | Scientific Literature | ||
| 9. | ALA4410701 | A | Half life in human liver microsomes at 1 uM in presence of NADPH generating system measured for 10 to 90 mins by LC-MS/MS analysis | Homo sapiens | 4 | microsome format | Scientific Literature | ||
| 10. | ALA4410702 | A | Clearance in human liver microsomes at 1 uM in presence of NADPH generating system measured for 10 to 90 mins by LC-MS/MS analysis | Homo sapiens | 4 | microsome format | Scientific Literature | ||
| 11. | ALA4410703 | F | Antidepressant activity in mouse assessed as decrease in immobility time at 10 mg/kg, po administrated for daily for 7 days measured 1 hr post last dose by forced swim test relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA4410704 | F | Antidepressant activity in mouse assessed as decrease in immobility time at 20 mg/kg, po administrated for daily for 7 days measured 1 hr post last dose by forced swim test relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA4410705 | F | Antidepressant activity in mouse assessed as decrease in immobility time at 40 mg/kg, po administrated for daily for 7 days measured 1 hr post last dose by forced swim test relative to control | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 14. | ALA4410706 | F | Antidepressant activity in mouse assessed as decrease in immobility time at 10 mg/kg, po administrated for daily for 7 days measured 1 hr post last dose by tail suspension test relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 15. | ALA4410707 | F | Antidepressant activity in mouse assessed as decrease in immobility time at 20 mg/kg, po administrated for daily for 7 days measured 1 hr post last dose by tail suspension test relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA4410708 | F | Antidepressant activity in mouse assessed as decrease in immobility time at 30 mg/kg, po administrated for daily for 7 days measured 1 hr post last dose by tail suspension test relative to control | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 17. | ALA5217326 | B | Inhibition of serotonin transporter in rat brain tissue assessed as inhibition of [3H]-5-hydroxytryptamine reuptake | Rattus norvegicus | 5 | tissue-based format | Scientific Literature | ||
| 18. | ALA5217327 | B | Displacement of [3H]8-OH-DAPT from 5-HT1A receptor in human HEK293 cells measured after 60 mins by scintillation counting method | Homo sapiens | 6 | cell-based format | Scientific Literature |
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