| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4424050 | A | Cytotoxicity against human HuH7 cells at 10 uM after 24 hrs by WST-1 assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 2. | ALA4424051 | F | Antiviral activity against HCV pseudo-particle infected in human HuH7 cells assessed as inhibition of HCV pseudo particles entry at 10 uM preincubated for 1 hr followed by viral infection and measured after 72 hrs by bright-glo luciferase reporter gene assay | Hepacivirus hominis | 11 | organism-based format | Scientific Literature | ||
| 3. | ALA4424052 | F | Antiviral activity against HCV sub-genomic replicon infected in human Huh7 cells at 10 uM added immediately with viral infection and measured after 24 hrs by bright-glo luciferase reporter gene assay relative to control | Hepacivirus hominis | 10 | organism-based format | Scientific Literature | ||
| 4. | ALA4424053 | F | Antiviral activity against HCV sub-genomic replicon infected in human Huh7-J20 cells after 24 hrs by bright-glo luciferase reporter gene assay | Hepacivirus hominis | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA4424054 | A | Cytotoxicity against human Huh7-J20 cells infected with HCV sub-genomic replicon assessed as reduction in cell viability up to 30 uM after 24 hrs by WST-1 assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4424055 | A | Cytotoxicity against human Huh7-J20 cells infected with HCV JFH-1 after 72 hrs by WST-1 assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4424056 | F | Antiviral activity against HCV JFH-1 infected in human Huh7-J20 cells after 72 hrs by SEAP based assay | Hepacivirus hominis | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4424057 | F | Antiviral activity against HCV sub-genomic replicon infected in human Huh7 cells at 10 uM added 24 hrs after viral infection and measured after 24 hrs by bright-glo luciferase reporter gene assay relative to control | Hepacivirus hominis | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4424058 | F | Antiviral activity against HCV sub-genomic replicon infected in human Huh7 cells after 2 to 24 hrs by bright-glo luciferase reporter gene assay | Hepacivirus hominis | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4424059 | F | Antiviral activity against HCV replication defective replicon infected in human Huh7 cells after 2 to 8 hrs by bright-glo luciferase reporter gene assay | Hepacivirus hominis | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4424060 | F | Antiviral activity against HCV replicon infected in human Huh7-J17 cells after 24 hrs by bright-glo luciferase reporter gene assay relative to control | Hepacivirus hominis | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4424061 | F | Antiviral activity against HCV replicon infected in human Huh7 cells assessed as reduction in NS5A level after 8 to 24 hrs by Western blot analysis | Hepacivirus hominis | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4424062 | F | Antiviral activity against HCV replicon infected in human Huh7 cells assessed as reduction in accumulation of unprocessed polyproteins after 8 to 24 hrs by Western blot analysis | Hepacivirus hominis | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4424063 | B | Inhibition of HCV IRES transfected in human Huh7 cells assessed as inhibition of IRES-mediated translation after 24 hrs by dual luciferase reporter gene assay relative to control | Hepacivirus hominis | 1 | cell-based format | Scientific Literature |
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