# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4368066 | Binding | Corrector activity at CFTR F508del mutant (unknown origin) expressed in rat FRT cells assessed as iodide influx preincubated for 18 to 24 hrs followed by compound wash out and addition of forskolin and genistein by fluorescence based assay | Homo sapiens | 6 | ALA4364316 | cell-based format | Scientific Literature | |
2. | ALA4368067 | Binding | Corrector activity at CFTR F508del mutant (unknown origin) expressed in rat FRT cells assessed as Vmax preincubated for 18 to 24 hrs followed by compound wash out and addition of forskolin and genistein by fluorescence based assay | Homo sapiens | 6 | ALA4364316 | cell-based format | Scientific Literature | |
3. | ALA4368068 | Binding | Potentiator activity at CFTR F508del mutant (unknown origin) expressed in rat FRT cells assessed as iodide influx preincubated for 18 to 24 hrs followed by compound wash out and subsequent compound and forskolin addition by fluorescence based assay | Homo sapiens | 6 | ALA4364316 | cell-based format | Scientific Literature | |
4. | ALA4368069 | Binding | Potentiator activity at CFTR F508del mutant (unknown origin) expressed in rat FRT cells assessed as Vmax preincubated for 18 to 24 hrs followed by compound wash out and subsequent compound and forskolin addition by fluorescence based assay | Homo sapiens | 6 | ALA4364316 | cell-based format | Scientific Literature | |
5. | ALA5231450 | Binding | Corrector activity at CFTR F508del mutant (unknown origin) expressed in rat FRT cells assessed as increase in iodide influx in presence of forskolin incubated for 24 hrs | Homo sapiens | 5 | ALA5230114 | cell-based format | Scientific Literature | |
6. | ALA5231451 | Binding | Corrector activity at CFTR F508del mutant (unknown origin) expressed in rat FRT cells assessed as increase in iodide influx by measuring Vmax in presence of forskolin incubated for 24 hrs | Homo sapiens | 5 | ALA5230114 | cell-based format | Scientific Literature | |
7. | ALA5231452 | Binding | Potentiation of CFTR F508del mutant (unknown origin) expressed in rat FRT cells assessed as increase in iodide influx in presence of forskolin incubated for 24 hrs | Homo sapiens | 5 | ALA5230114 | cell-based format | Scientific Literature | |
8. | ALA5231453 | Binding | Potentiation of CFTR F508del mutant (unknown origin) expressed in rat FRT cells assessed as increase in iodide influx by measuring Vmax in presence of forskolin incubated for 24 hrs | Homo sapiens | 5 | ALA5230114 | cell-based format | Scientific Literature |