# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4414789 | B | Inhibition of TYK2/JAK2 in IL23-stimulated human Kit225 cells by steady-glo luciferase assay | Homo sapiens | 25 | ALA4414548 | assay format | Scientific Literature | |
2. | ALA4414790 | B | Inhibition of TYK2/JAK1 in IFNalpha-stimulated human Kit225 cells by steady-glo luciferase assay | Homo sapiens | 27 | ALA4414548 | assay format | Scientific Literature | |
3. | ALA4414793 | B | Inhibition of TYK2 JH2 domain in human whole blood assessed as inhibition of IFNalpha-induced STAT5 phosphorylation preincubated for 1 hr followed by IFNalpha stimulation and measured after 15 mins by fluorescence assay | Homo sapiens | 20 | ALA4414548 | tissue-based format | Scientific Literature | |
4. | ALA4414795 | A | Permeability across apical to basolateral side in human Caco2 cells | Homo sapiens | 17 | ALA4414548 | cell-based format | Scientific Literature | |
5. | ALA4414796 | A | Efflux ratio of permeability in human Caco2 | Homo sapiens | 17 | ALA4414548 | cell-based format | Scientific Literature | |
6. | ALA4414830 | A | Inhibition of cKIT (unknown origin) | Homo sapiens | 9 | ALA4414548 | single protein format | Scientific Literature | |
7. | ALA4414831 | B | Inhibition of human ERG by fluorescence polarization assay | Homo sapiens | 7 | ALA4414548 | single protein format | Scientific Literature |