# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4407835 | Physicochemical | n-octanol/water partition coefficient, log P of the compound by shake flask method based HPLC analysis | 1 | ALA4406821 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA4407836 | Binding | Inhibition of recombinant full length human CDK4/Cyclin D3 using Rb-fragmen as substrate at 1 uM incubated for 40 mins by [gamma-33P]-ATP based radiometric assay relative to control | Homo sapiens | 33 | ALA4406821 | protein complex format | Scientific Literature | |
3. | ALA4407837 | Binding | Inhibition of recombinant human VEGFR2 (790 to end residues) using myelin ba as substrate at 1 uM incubated for 40 mins by [gamma-33P]-ATP based radiometric assay relative to control | Homo sapiens | 33 | ALA4406821 | single protein format | Scientific Literature | |
4. | ALA4407838 | Functional | Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay | Homo sapiens | 9 | ALA4406821 | cell-based format | Scientific Literature | |
5. | ALA4407839 | Functional | Antiproliferative activity against human T47D cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay | Homo sapiens | 9 | ALA4406821 | cell-based format | Scientific Literature | |
6. | ALA4407840 | Functional | Antiproliferative activity against human SiHa cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4406821 | cell-based format | Scientific Literature | |
7. | ALA4407841 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4406821 | cell-based format | Scientific Literature | |
8. | ALA4407842 | Functional | Antiproliferative activity against HUVEC cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4406821 | cell-based format | Scientific Literature | |
9. | ALA4407843 | Physicochemical | n-octanol/phosphate buffered saline partition coefficient, log D of the compound measured at pH 7.4 by shake flask method based HPLC analysis | 1 | ALA4406821 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA4407844 | Functional | Antiangiogenic activity against HUVEC cells assessed as reduction in tube formation at 20 to 40 nM incubated for 6 hrs by light microscopy | Homo sapiens | 2 | ALA4406821 | cell-based format | Scientific Literature | |
11. | ALA4407845 | Binding | Inhibition of VEGFR2 in HUVEC cells assessed as reduction in VEGFR2 phosphorylation at 20 to 40 nM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4406821 | cell-based format | Scientific Literature | |
12. | ALA4407846 | Binding | Inhibition of VEGFR2 in HUVEC cells assessed as reduction in STAT3 phosphorylation at 20 to 40 nM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4406821 | cell-based format | Scientific Literature | |
13. | ALA4407847 | Binding | Inhibition of VEGFR2 in HUVEC cells assessed as reduction in Akt phosphorylation at 20 to 40 nM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4406821 | cell-based format | Scientific Literature | |
14. | ALA4407848 | Binding | Inhibition of VEGFR2 in HUVEC cells assessed as reduction in Src phosphorylation at 20 to 40 nM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4406821 | cell-based format | Scientific Literature | |
15. | ALA4407849 | Binding | Inhibition of VEGFR2 in HUVEC cells assessed as reduction in ERK1/2 phosphorylation at 20 to 40 nM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4406821 | cell-based format | Scientific Literature | |
16. | ALA4407850 | Functional | Antiangiogenic activity in Matrigel plug angiogenic BALB/c mouse assessed as reduction in blood vessel formation at 10 to 20 mg/kg, sc measured after 10 days by Matrigel plug assay | Mus musculus | 1 | ALA4406821 | organism-based format | Scientific Literature | |
17. | ALA4407852 | Functional | Inhibition of colony formation in human MDA-MB-231 cells at 20 to 40 nM incubated for 5 days by crystal violet staining based light microscopy | Homo sapiens | 1 | ALA4406821 | cell-based format | Scientific Literature | |
18. | ALA4407853 | Functional | Inhibition of colony formation in human T47D cells at 20 to 40 nM incubated for 5 days by crystal violet staining based light microscopy | Homo sapiens | 1 | ALA4406821 | cell-based format | Scientific Literature | |
19. | ALA4407854 | Functional | Inhibition of colony formation in human SiHa cells at 40 to 80 nM incubated for 5 days by crystal violet staining based light microscopy | Homo sapiens | 1 | ALA4406821 | cell-based format | Scientific Literature | |
20. | ALA4407855 | Functional | Inhibition of colony formation in human HeLa cells at 40 to 80 nM incubated for 5 days by crystal violet staining based light microscopy | Homo sapiens | 1 | ALA4406821 | cell-based format | Scientific Literature |