# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4361881 | B | Protac activity at CRBN/IRAK4 in human PBMC assessed as induction of degradation of IRAK4 incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 2 | protein format | Scientific Literature | ||
2. | ALA4361896 | B | Binding affinity to human IRK4 using myelin basic protein as substrate by [gamma-33P]-ATP assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
3. | ALA4361897 | B | Binding affinity to human IRK1 using myelin basic protein as substrate by [gamma-33P]-ATP assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
4. | ALA4361898 | P | Chromatographic hydrophobicity index, log D of compound at pH 7.4 | 9 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA4361899 | B | Protac activity at VHL/IRAK4 in human THP-1 cells assessed as induction of degradation of IRAK4 at 0.1 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 7 | cell-based format | Scientific Literature |