# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4424072 | Functional | Antitrypanosomal activity against Trypanosoma brucei brucei Squib 427 after 48 hrs by alamar blue assay | Trypanosoma brucei brucei | 29 | ALA4422651 | organism-based format | Scientific Literature | |
2. | ALA4424073 | Functional | Antitrypanosomal activity against Trypanosoma brucei rhodesiense STIB-900 after 48 hrs by alamar blue assay | Trypanosoma brucei rhodesiense | 29 | ALA4422651 | organism-based format | Scientific Literature | |
3. | ALA4424074 | ADME | Cytotoxicity against human MRC5 cells assessed as reduction in cell viability after 3 days by resazurin dye-based assay | Homo sapiens | 30 | ALA4422651 | cell-based format | Scientific Literature | |
4. | ALA4424075 | Toxicity | Selectivity index, ratio of EC50 for human MRC5 cells to EC50 for Trypanosoma brucei brucei Squib 427 | 29 | ALA4422651 | assay format | Scientific Literature | ||
5. | ALA4424076 | Toxicity | Selectivity index, ratio of EC50 for human MRC5 cells to EC50 for Trypanosoma brucei rhodesiense STIB-900 | 29 | ALA4422651 | assay format | Scientific Literature | ||
6. | ALA4424084 | Functional | Antitrypanosomal activity against nifurtimox-sensitive Trypanosoma cruzi Tulahuen CL2 harboring beta-galactosidase infected in human MRC5 cells after 7 days by resazurin dye-based assay | Trypanosoma cruzi | 29 | ALA4422651 | organism-based format | Scientific Literature | |
7. | ALA4424086 | Binding | Inhibition of [3H]-adenosine transport at Trypanosoma brucei Adenosine transporter P1 expressed in pentamidine/diminazene/melaminophenyl arsenical resistant Trypanosoma brucei B48 bloodstream forms after 60 secs by scintillation counting analysis | Trypanosoma brucei | 5 | ALA4422651 | assay format | Scientific Literature | |
8. | ALA4424087 | Binding | Inhibition of [3H]-adenosine transport at Trypanosoma brucei Adenosine transporter P2 expressed in pentamidine/diminazene/melaminophenyl arsenical resistant Trypanosoma brucei B48 bloodstream forms after 60 secs by scintillation counting analysis | Trypanosoma brucei | 5 | ALA4422651 | assay format | Scientific Literature |