| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4432252 | B | Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-OG as co-substrate by TR-FRET assay | Homo sapiens | 15 | single protein format | Scientific Literature | ||
| 2. | ALA4432253 | P | Dissociation constant, pKa of the compound | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4432256 | B | Inhibition of full length human KDM4C using biotinylated H2N-ARTKQTAR(KMe3)STGGKAPRKQLA-NTPEGBiot as substrate after 30 mins using 3 uM of 2-OG as co-substrate by TR-FRET assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 4. | ALA4432257 | B | Inhibition of full length human KDM2B using biotinylated H2N-RKSAPATGGV(KMe2)KPHRYRPGTV-NTPEGBiot as substrate after 2 hrs using 0.3 uM of 2-OG as co-substrate by TR-FRET assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 5. | ALA4432258 | B | Selectivity ratio of IC50 for full length human KDM4C to IC50 for full length human KDM5A | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA4432259 | B | Selectivity ratio of IC50 for full length human KDM2B to IC50 for full length human KDM5A | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 7. | ALA4432265 | B | Ratio of IC50 for full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate and 10 uM of 2-OG as co-substrate to IC50 for full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate and 1 uM of 2-OG as co-substrate | Homo sapiens | 1 | single protein format | Scientific Literature |
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